What is a healthy omega-6 (fatty acid) level in bloodwork for a 58-year-old male?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: April 9, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

From the Guidelines

A healthy omega-6 level for a 58-year-old male should generally maintain an omega-6 to omega-3 ratio between 1:1 and 4:1, with total omega-6 fatty acids comprising approximately 5-10% of daily caloric intake. While specific blood level targets vary by laboratory, maintaining this balance is more important than focusing on absolute omega-6 levels alone 1. Most Americans consume excessive omega-6 fatty acids (often 15:1 or higher ratio), which can promote inflammation when significantly imbalanced. To achieve healthier levels, reduce consumption of processed foods, vegetable oils (corn, soybean, sunflower), and fried foods while increasing omega-3 sources like fatty fish, flaxseeds, and walnuts.

Key Considerations

  • The risk of CAD is reduced by 2–3% when 1% of energy intake from saturated fatty acids is replaced by polyunsaturated fatty acids, which include omega-6 fatty acids 1.
  • Polyunsaturated fatty acids lower LDL-C levels, and to a lesser extent HDL-C levels, when they replace saturated fatty acids 1.
  • An unbalanced ratio of omega-6 to omega-3 fatty acids favoring omega-6 can lead to increased activation of the arachidonic acid pathway, with resulting increases in rates of thrombosis, vasospasm, cancer, obesity, and allergic and inflammatory disorders 1.

Recommendations

  • Consider having both omega-6 and omega-3 levels measured together for a more meaningful assessment.
  • If concerned about your specific levels, consult with a healthcare provider who can interpret your results based on your individual health profile, as optimal levels may vary depending on existing health conditions, medications, and overall inflammatory status.
  • Increasing consumption of foods high in omega-3 fatty acids (e.g., fish, nuts, canola oil, green vegetables) while limiting the use of corn and vegetable oils can increase the ratio of omega-3 to omega-6 fatty acids, leading to decreased inflammation and other health benefits 1.

From the Research

Omega-6 Fatty Acid Levels in Bloodwork

  • The ideal level of omega-6 fatty acids in bloodwork for a 58-year-old male is not explicitly stated in the provided studies 2, 3, 4, 5, 6.
  • However, it is mentioned that a high omega-6/omega-3 ratio, as found in Western diets, can promote the pathogenesis of chronic diseases, including cardiovascular disease 6.
  • The studies suggest that increasing intake of omega-6 fatty acids, such as arachidonic acid (ARA) or linoleic acid (LA), may not necessarily increase inflammation in healthy adults 2, 4.
  • On the other hand, a high omega-6 fatty acid diet may inhibit the anti-inflammatory effects of omega-3 fatty acids 2, 3.

Importance of Omega-6/Omega-3 Ratio

  • The omega-6/omega-3 ratio is considered important in determining the risk of chronic diseases, with a high ratio promoting disease pathogenesis 6.
  • The ideal ratio of omega-6 to omega-3 fatty acids is not specified in the provided studies, but it is suggested that a balanced intake of both types of fatty acids is important for maintaining good health 4, 5.
  • Omega-3 fatty acids, particularly eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), have been shown to have anti-inflammatory effects and may help reduce the risk of chronic diseases 3, 4, 5, 6.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Omega-6 fatty acids and inflammation.

Prostaglandins, leukotrienes, and essential fatty acids, 2018

Research

Omega-3 fatty acids EPA and DHA: health benefits throughout life.

Advances in nutrition (Bethesda, Md.), 2012

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.