What antibiotic is recommended for exposure to goose feces?

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Exposure to Goose Feces: No Routine Antibiotic Prophylaxis Indicated

Routine antibiotic prophylaxis is not recommended for simple exposure to goose feces without evidence of infection or high-risk wound contamination.

When Antibiotics Are NOT Needed

  • Simple environmental exposure (stepping in, touching, or incidental contact with goose droppings) does not warrant antibiotic therapy, as the risk of bacterial infection from fecal contact alone is extremely low without a breach in skin integrity 1

  • Intact skin provides an effective barrier against bacterial pathogens commonly found in waterfowl feces, including Salmonella, Campylobacter, and E. coli species 1

  • Hand washing with soap and water is the primary intervention for fecal exposure without wounds 1

When Antibiotics ARE Indicated

For Contaminated Wounds or Bites

If goose feces contaminated an open wound or if a goose bite occurred with fecal exposure, treatment follows bite wound protocols:

  • First-line therapy: Amoxicillin-clavulanate 875/125 mg twice daily for 7-10 days provides optimal coverage against polymicrobial flora including aerobic and anaerobic bacteria 2, 3, 4

  • For penicillin allergy: Doxycycline 100 mg twice daily is the preferred alternative, though it has limited activity against some streptococci 2, 3

  • Severe infections requiring hospitalization: Ampicillin-sulbactam 1.5-3.0 g IV every 6-8 hours 2, 4

For Gastroenteritis Symptoms

If diarrheal illness develops after exposure (typically 12-72 hours post-exposure):

  • Campylobacter infection (most common from waterfowl): Azithromycin 500 mg once daily for 3 days is superior to fluoroquinolones due to widespread ciprofloxacin resistance 5

  • Salmonella gastroenteritis: Antibiotics are NOT routinely recommended for immunocompetent patients, as treatment may prolong fecal shedding 1

  • Exceptions requiring treatment: Patients <6 months or >50 years old, immunocompromised status, prosthetic devices, or severe illness warrant ciprofloxacin 500 mg twice daily for 5-7 days (if susceptible) or azithromycin 1, 6

Critical Pitfalls to Avoid

  • Do not prescribe antibiotics for asymptomatic fecal exposure - this promotes resistance without clinical benefit 1

  • Avoid fluoroquinolones as first-line for suspected Campylobacter - resistance rates exceed 50% in many regions, making azithromycin the superior choice 5

  • Do not use antimotility agents (loperamide, diphenoxylate) if bloody diarrhea or high fever develops, as this increases risk of complications with enterohemorrhagic E. coli 1

Adjunctive Measures

  • Immediate wound care: Thorough irrigation with sterile saline for any contaminated wounds 2, 3

  • Tetanus prophylaxis: Update if not current within 10 years for any wound contamination 2, 3

  • Hydration: Oral rehydration is the cornerstone of gastroenteritis management regardless of antibiotic use 1

Special Populations

  • Immunocompromised patients: Lower threshold for antibiotic treatment of gastroenteritis (TMP-SMZ or fluoroquinolones for 14 days or longer if relapsing) 1

  • Pregnant women: Treat Salmonella gastroenteritis to prevent extraintestinal spread; use ampicillin, cefotaxime, ceftriaxone, or TMP-SMZ (avoid fluoroquinolones) 1

  • Children <3 months: Treat any Salmonella gastroenteritis to prevent bacteremia; options include TMP-SMZ, ampicillin, cefotaxime, or ceftriaxone 1

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Treatment of Bacterial Infections Following Ectoparasite Bites

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Antibiotic Prophylaxis for Cat Bites

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Antibiotic Therapy for Turtle Bites

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Use of azithromycin for the treatment of Campylobacter enteritis in travelers to Thailand, an area where ciprofloxacin resistance is prevalent.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1995

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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