Prednisone Dosing for a 14-Year-Old with Bronchitis
Prednisone is not recommended for acute bronchitis in a 14-year-old patient, as systemic corticosteroids have no proven benefit in this condition and should not be used routinely. 1
Key Distinction: Acute Bronchitis vs. Other Conditions
The critical first step is determining what type of "bronchitis" you're treating, as this fundamentally changes management:
Acute Bronchitis (Most Common)
- No steroids indicated - The clinical course is self-limited, resolving spontaneously in approximately 10 days, though cough may persist longer 1
- Purulent sputum does NOT indicate bacterial superinfection and does not justify steroid treatment 1
- Antibiotics are also not recommended for acute bronchitis in otherwise healthy patients 1
Protracted Bacterial Bronchitis (Chronic Wet Cough)
If the 14-year-old has had a wet/productive cough for >4 weeks without underlying disease:
- Antibiotics, not steroids, are the treatment of choice 2
- Recommend 2 weeks of antibiotics targeting common respiratory bacteria (Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis) 2
- If cough persists after 2 weeks of appropriate antibiotics, extend treatment for an additional 2 weeks 2
- Corticosteroids are not part of the management algorithm for protracted bacterial bronchitis 2
Asthma Exacerbation (Misdiagnosed as "Bronchitis")
If the patient actually has asthma presenting with cough and wheezing:
- Prednisone 1-2 mg/kg/day (maximum 60 mg/day) for 3-10 days is appropriate 2
- This is typically 40-60 mg daily as a single dose or divided into 2 doses 2
Postinfectious Cough
If cough has persisted 3-8 weeks following an acute respiratory infection:
- First-line: Consider inhaled ipratropium 2
- Second-line: Inhaled corticosteroids if cough adversely affects quality of life and persists despite ipratropium 2
- For severe paroxysms only: Prednisone 30-40 mg/day for a short, finite period after ruling out other common causes (upper airway cough syndrome, asthma, GERD) 2
Common Pitfalls to Avoid
- Mistaking acute bronchitis for asthma exacerbation - The presence of wheezing alone does not justify steroids in acute bronchitis 1
- Prescribing steroids based on purulent sputum - This is not an indication for steroid therapy in acute bronchitis 1
- Using steroids to shorten illness duration - Evidence shows no benefit for this purpose in acute bronchitis 1
- Confusing bronchiolitis (age <2 years) with bronchitis - Bronchiolitis also does not benefit from steroids 3, 4
Clinical Algorithm
- Duration <3 weeks with acute onset: Acute bronchitis → No steroids, supportive care only 1
- Duration >4 weeks with wet cough: Protracted bacterial bronchitis → Antibiotics, not steroids 2
- History of asthma with wheezing: Asthma exacerbation → Prednisone 1-2 mg/kg/day 2
- Duration 3-8 weeks post-infection with severe paroxysms: Postinfectious cough → Consider prednisone 30-40 mg/day only after other causes ruled out 2