Signs and Symptoms of Bacterial Vaginosis
Bacterial vaginosis presents with four cardinal features: homogeneous white vaginal discharge, fishy odor (especially after intercourse or menses), vaginal pH >4.5, and clue cells on microscopy—though approximately 50% of affected women remain completely asymptomatic. 1, 2
Clinical Presentation
Symptomatic Disease (50% of cases)
Vaginal discharge characteristics:
- Homogeneous, thin, white or gray discharge that smoothly coats the vaginal walls (not thick or clumpy) 1, 2
- Non-inflammatory in nature—the vaginal walls typically lack erythema or irritation 1
Characteristic odor:
- Fishy or musty vaginal odor, often described as amine-like 3, 4
- Odor becomes more pronounced after intercourse or during menstruation due to alkaline pH changes 2
- The "whiff test" (fishy odor immediately after applying 10% KOH to discharge) is positive 1, 2
Additional symptoms:
Asymptomatic Disease (50% of cases)
A critical clinical pitfall is that up to half of women meeting diagnostic criteria for BV report no noticeable symptoms whatsoever. 1, 2, 5 This asymptomatic presentation is particularly important because:
- These women remain at risk for serious complications including pelvic inflammatory disease, endometritis, and adverse pregnancy outcomes 2
- Asymptomatic BV increases susceptibility to sexually transmitted infections 2
- Women undergoing invasive gynecological procedures require screening even without symptoms 2
Diagnostic Findings on Examination
Microscopic findings:
- Clue cells (vaginal epithelial cells with adherent bacteria obscuring cell borders) on wet mount examination 1, 2
- Absence of inflammatory cells—this distinguishes BV from trichomoniasis 1
- Shift from normal Lactobacillus-dominant flora to mixed anaerobic bacteria on Gram stain 1, 2
Physical examination findings:
- Vaginal pH greater than 4.5 (normal is 3.8-4.5) 1, 2
- Absence of vulvar inflammation or erythema (helps differentiate from candidiasis) 1
- Discharge that is thin and adherent rather than thick and cottage cheese-like 2, 4
Key Clinical Distinctions
What BV is NOT:
- BV does not cause vulvar itching, burning, or significant irritation as the primary complaint (these suggest candidiasis) 4
- BV does not produce a profuse, yellow-green, frothy discharge (this suggests trichomoniasis) 4
- BV does not cause vulvar or vaginal erythema or inflammation 1
- BV does not cause painful intercourse as a primary symptom 4
Important Clinical Considerations
The absence of symptoms does not exclude BV diagnosis—objective diagnostic criteria must be applied in high-risk populations including pregnant women, women planning pregnancy, and those undergoing invasive procedures. 2, 6 Women who have never been sexually active are rarely affected, though BV is associated with multiple sexual partners 1, 2. The condition has a high recurrence rate of 50-80% within one year, so patients should be counseled about potential symptom return 2.