Can splenic embolization cause ileus?

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Last updated: December 28, 2025View editorial policy

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Can Splenic Embolization Cause Ileus?

Yes, splenic embolization can cause ileus as part of post-embolization syndrome (PES), which occurs in up to 90% of pediatric patients and is also seen in adults, though the syndrome is typically self-limited and resolves within 6-9 days. 1

Post-Embolization Syndrome: The Primary Mechanism

Post-embolization syndrome is a well-recognized complication following splenic artery embolization that includes ileus as a core component. The syndrome consists of: 1

  • Abdominal pain
  • Nausea
  • Ileus (the specific concern in your question)
  • Fever

Clinical Course and Prognosis

The ileus associated with splenic embolization has favorable characteristics: 1

  • Self-limited: Resolves spontaneously without intervention in most cases
  • Duration: Typically resolves within 6-9 days
  • Incidence: Occurs in approximately 90% of pediatric patients undergoing angiography/angioembolization (AG/AE)
  • Mortality: Rarely associated with major complications or death

Additional Complications to Monitor

While ileus is part of the expected post-embolization syndrome, clinicians should remain vigilant for other complications: 1

  • Pleural effusion (9% incidence)
  • Pneumonia (9% incidence)
  • Coil migration (4.5% incidence)
  • Splenic abscess 2, 3
  • Splenic infarction 2, 3
  • Contrast-induced renal insufficiency 2, 3

Clinical Management Approach

When ileus develops after splenic embolization: 1

  • Expect it: Recognize that ileus is part of the normal post-procedure course in the majority of patients
  • Conservative management: Supportive care is typically sufficient given the self-limited nature
  • Timeline: Anticipate resolution within 6-9 days
  • Red flags: Investigate for alternative diagnoses if symptoms persist beyond this timeframe or worsen significantly

Important Caveats

The evidence base for post-embolization syndrome comes primarily from pediatric trauma populations, though the syndrome is recognized in adults as well. 1 The World Society of Emergency Surgery guidelines specifically note that mortality and major complications are rarely reported following AG/AE, positioning ileus as an expected but benign complication rather than a serious adverse event. 1

Distal embolization techniques are associated with higher complication rates (24% vs 6% for proximal embolization alone), though this primarily refers to major complications like abscess and infarction rather than post-embolization syndrome specifically. 2

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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