Management of Seizure in a 10-Year-Old Child
Immediate Assessment and Classification
The first critical step is determining whether this is a febrile or afebrile seizure by checking temperature immediately, as this fundamentally changes your diagnostic and management approach 1.
For Febrile Seizures (Temperature Present)
- Simple febrile seizures (lasting <15 minutes, generalized, single episode in 24 hours) require NO routine anticonvulsant therapy 2.
- The primary goal is identifying the fever source, not preventing seizure recurrence 1.
- Lumbar puncture is NOT routinely indicated unless specific red flags exist 2, 1:
For Afebrile (Unprovoked) Seizures
- EEG is recommended as part of the neurodiagnostic evaluation for a first unprovoked seizure 1, 3.
- Neuroimaging with MRI is the preferred study, particularly for focal seizures 1, 3.
- Blood glucose should be checked if the child is still convulsing or unrousable 2.
Acute Management During Active Seizure
- Position the child on their side to maintain airway 1.
- Benzodiazepines are indicated if the seizure lasts >5 minutes or does not terminate spontaneously 1.
- Midazolam (buccal, intranasal, or intramuscular) is preferred when IV access is unavailable 4.
- Lorazepam or diazepam are suitable IV agents 4.
Long-Term Anticonvulsant Therapy Decisions
For Simple Febrile Seizures:
Neither continuous nor intermittent anticonvulsant therapy is recommended, as the risks of medication toxicity outweigh the minimal risks of simple febrile seizures 2, 1.
- Phenobarbital, primidone, valproic acid, and intermittent diazepam are effective at reducing recurrence but have unacceptable adverse effects relative to the benign nature of simple febrile seizures 2.
- Antipyretics (acetaminophen) should be used for comfort and preventing dehydration, NOT for seizure prevention, as they do not prevent febrile seizure recurrence 2, 1.
- Physical cooling methods (cold bathing, tepid sponging) are not recommended as they cause discomfort 2.
For First Unprovoked Seizures:
Emergency physicians need not initiate antiepileptic medication in the ED for patients with a first unprovoked seizure without evidence of brain disease or injury 2.
- Treatment may be initiated or deferred in coordination with other providers for patients with remote history of brain disease or injury (stroke, trauma, tumor) 2.
- For patients with 2-3 recurrent unprovoked seizures, the risk of further seizures increases substantially (approximately 75% within 5 years), making treatment more appropriate 2.
- The number needed to treat to prevent one seizure recurrence in the first year is approximately 5 for symptomatic seizures 2.
Prognosis and Parent Counseling
The prognosis for simple febrile seizures is excellent with no long-term adverse effects on IQ, academic performance, or neurocognitive function 2, 1.
Specific Risk Counseling:
- Risk of developing epilepsy after simple febrile seizures is approximately 1% by age 7 years (same as general population) 2, 1.
- Children with multiple simple febrile seizures, age <12 months at first seizure, and family history of epilepsy have higher risk (2.4% by age 25) 2.
- Recurrence risk is approximately 30% overall, but increases to 50% in children <12 months at first seizure 2, 1.
- Children with first-degree relative with febrile seizures have nearly 50% recurrence risk 2.
- Death during a simple febrile seizure has never been reported 2.
Hospital Admission Criteria
Admission is NOT routinely required for patients who have returned to clinical baseline 2.
Factors favoring admission:
- Complex convulsion lasting >20 minutes (neuroimaging typically performed first) 2.
- Not returned to baseline neurological status 2.
- Concern for meningitis or other serious infection 2.
- Social factors preventing adequate home observation 2.
Key Pitfalls to Avoid
- Do not routinely perform lumbar puncture on all children with febrile seizures—this is outdated practice 2, 1.
- Do not prescribe continuous anticonvulsants for simple febrile seizures—the toxicity outweighs any benefit 2, 1.
- Do not tell parents that antipyretics prevent seizure recurrence—they provide comfort only 2, 1.
- EEG is not helpful after a single simple febrile convulsion and does not guide treatment or prognosis 2.