How to get a brachial plexus Magnetic Resonance Imaging (MRI) approved for a patient?

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Last updated: December 29, 2025View editorial policy

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How to Get Brachial Plexus MRI Approved

To get a brachial plexus MRI approved, you must order it using the correct CPT code based on the clinical indication: use MRI chest for suspected Pancoast tumor, MRI orbit/face/neck for head and neck cancers extending to the brachial plexus, or MRI upper extremity for shoulder girdle/axillary tumors or nonspecific brachial plexopathy symptoms. 1

Understanding the CPT Coding Challenge

The fundamental issue is that no specific CPT code exists for brachial plexus MRI, despite having ICD-10 codes for brachial plexus disorders. 1 The American College of Radiology's Economics Committee on Coding & Nomenclature established that the appropriate CPT code depends entirely on your clinical indication. 1

Selecting the Correct CPT Code

For Suspected Malignancy:

  • MRI chest (focusing on brachial plexus): Use for apical lung cancers (Pancoast tumors) 1
  • MRI orbit, face and neck: Use for head and neck cancers extending to thyroid level, including brachial plexus involvement 1

For Nontraumatic Plexopathy Without Malignancy:

  • MRI upper extremity: Use for shoulder girdle/axillary tumors or nonspecific brachial plexopathy symptoms requiring nerve imaging 1

Critical Documentation Requirements

Your authorization request must emphasize that dedicated brachial plexus imaging differs fundamentally from routine neck, chest, spine, or upper extremity MRI protocols. 1, 2 Standard protocols are inadequate and should not be considered alternatives to dedicated plexus imaging. 1

Specify These Technical Requirements:

  • Orthogonal views through the oblique planes of the plexus 1
  • T1-weighted sequences 1
  • T2-weighted sequences 1
  • Fat-saturated T2-weighted or STIR sequences 1, 2
  • Fat-saturated T1-weighted postcontrast sequences (when contrast indicated) 1, 2

Clinical Justification Strategy

Document Plexopathy Symptoms (Not Radiculopathy):

  • Neuropathic pain in multiple peripheral nerve distributions (not dermatomal) 1
  • Weakness, sensory loss, and flaccid loss of reflexes in C5-T1 distribution 1
  • Dysesthesia, burning, or electric sensations in multiple nerve territories 1

Critical distinction: If symptoms follow a single dermatomal distribution, this suggests radiculopathy rather than plexopathy, and different imaging is appropriate. 1

State That MRI Is the Gold Standard:

  • MRI is the mainstay of plexus imaging with superior soft-tissue contrast and spatial resolution 1, 2
  • MRI provides superior definition of intraneural anatomy and localizes pathologic lesions when electrodiagnostic findings are nonspecific 1
  • MRI is the most accurate method to determine whether masses are intrinsic or extrinsic to plexus nerves 1

Differential Diagnosis to Include

List potential etiologies that MRI can identify:

  • Intrinsic nerve sheath tumors (schwannomas, neurofibromas) 1
  • Malignant peripheral nerve sheath tumors (14% of neurogenic tumors) 1
  • Inflammatory conditions (Parsonage-Turner syndrome/brachial neuritis) 2
  • Infectious, autoimmune, or idiopathic neuropathies 1
  • Extrinsic compression from adjacent structures 1
  • Chronic inflammatory demyelinating polyneuropathy 1

Common Pitfalls to Avoid

Do Not Accept These Substitutions:

  • Routine neck MRI - inadequate for plexus evaluation 1, 2
  • Routine chest MRI - inadequate for plexus evaluation 1, 2
  • Cervical spine MRI - inadequate for plexus evaluation 1, 2
  • Standard upper extremity MRI - inadequate without dedicated plexus protocol 1, 2

Emphasize Protocol Specificity:

State explicitly that the study requires MR neurography techniques with high-resolution T2-weighted sequences of peripheral nerves, which are routinely performed in dedicated brachial plexus protocols but not in standard regional imaging. 1

When Contrast Is Needed

Order MRI without and with IV contrast when evaluating for:

  • Suspected intrinsic versus extrinsic nerve masses 1, 2
  • Known or suspected malignancy 2
  • Inflammatory or infectious etiologies 2

Alternative Imaging If MRI Denied

If MRI is contraindicated or denied:

  • CT neck with IV contrast offers the next highest level of anatomic visualization 1, 2
  • FDG-PET/CT is appropriate only for known malignancy or post-treatment syndrome 1, 2

Field Strength Considerations

  • Request 1.5 Tesla if metal hardware is present in the area to reduce artifact 1, 2
  • 3 Tesla may provide superior spatial resolution and contrast when no metal is present 1, 3

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Brachial Plexus Injury Diagnosis and Management

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Three-dimensional MR imaging of the brachial plexus.

Seminars in musculoskeletal radiology, 2015

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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