From the Guidelines
To increase vitamin D levels, consider taking a vitamin D supplement, typically vitamin D3 (cholecalciferol), which is more effective than vitamin D2, with a common supplementation dose ranging from 1,000-2,000 IU daily, as recommended by the Institute of Medicine 1. For adults, the optimal blood levels of vitamin D are typically between 30-50 ng/mL, and regular blood tests can help monitor these levels. Some key points to consider when increasing vitamin D levels include:
- Spending 15-30 minutes in direct sunlight several times per week with exposed skin can help trigger vitamin D production in the body.
- Including vitamin D-rich foods in the diet, such as fatty fish, egg yolks, cheese, and fortified products like milk, orange juice, and cereals, can also help increase vitamin D levels.
- Vitamin D is fat-soluble, so taking it with a meal containing some fat can improve absorption.
- People with severe deficiency may require higher prescription doses initially, and it is essential to consult with a healthcare professional to determine the best course of treatment.
- The USPSTF has published recommendations on the use of vitamin D supplementation for the prevention of falls and fractures, and vitamin supplementation for the prevention of cardiovascular disease or cancer, which can be found at www.uspreventiveservicestaskforce.org 1. It is crucial to note that vitamin D toxicity is uncommon but may occur with daily doses of more than 50,000 IU per day that produce 25(OH)D levels larger than 150 ng/mL, as stated in the NCCN task force report 1. Overall, increasing vitamin D levels is essential for maintaining calcium absorption, bone health, immune function, and preventing various chronic diseases, making adequate levels crucial for overall health.
From the FDA Drug Label
Vitamin D3 50,000 IU is essential for absorption of calcium and necessary for healthy bones and a healthy immune system. DIRECTIONS: Take 0ne (1) capsule each week, or as directed by your physician. To increase vitamin D, take one capsule of Cholecalciferol (50,000 IU) per week, or as directed by a physician 2.
- Key points:
- Take with food
- Store in a cool, dry place, protected from light Note: It is essential to follow the recommended dosage and consult a physician for personalized advice.
From the Research
Increasing Vitamin D Levels
To increase vitamin D levels, several options are available, including supplementation and sun exposure. The following points highlight the key findings from various studies:
- Vitamin D supplementation can be effective in increasing vitamin D levels, with different dosages and forms (D2 and D3) available 3, 4, 5, 6.
- A study comparing the effects of a 10-day course of high-dose calciferol (D3) versus a single mega dose of ergocalciferol (D2) found that the D3 regimen was more effective in correcting vitamin D deficiency 3.
- Another study found that a daily dose of 2,000 IU of vitamin D3 was effective in maintaining vitamin D levels within the recommended range in healthy young adults 4.
- A review of the evidence argued for a daily dose of 2,000 IU (50 µg) of vitamin D3 to prevent and treat vitamin D deficiency in adults 5.
- Vitamin D supplementation has been linked to various health benefits, including improved musculoskeletal health and reduced risk of certain diseases 6.
Forms of Vitamin D
The two main forms of vitamin D are:
- D2 (ergocalciferol): less effective and may enhance the degradation of 25-hydroxyvitamin D3 (25[OH]D3) metabolite 3.
- D3 (cholecalciferol): more effective and recommended for supplementation 3, 4, 5.
Dosage and Administration
The optimal dosage and administration of vitamin D supplementation vary depending on the individual's needs and health status. Key findings include:
- A daily dose of 2,000 IU of vitamin D3 may be sufficient to maintain vitamin D levels within the recommended range 4, 5.
- Higher doses (4,000-8,000 IU/day) may be more effective for certain individuals, but regular monitoring of vitamin D levels is essential 4.
- A cumulative dose of at least 600,000 IU administered over several weeks may be necessary to replenish vitamin D stores in individuals with documented deficiency 6.