What is the typical absorption rate of absorbable sutures?

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Absorption Timeline for Absorbable Sutures

Slowly absorbable sutures (the recommended type for most surgical closures) complete absorption between 90-119 days, while maintaining critical tensile strength for 2-4 weeks during the wound healing period. 1, 2

Absorption Rates by Suture Type

Rapidly Absorbable Sutures

  • Vicryl Rapide: Loses tensile strength rapidly, with strength reduced to 14 N by day 42 from an initial 195 N 3
  • Standard braided absorbables (Vicryl, Dexon Plus): Half-life tensile strength of approximately 2 weeks, losing most strength within 60 days 4

Slowly Absorbable Sutures (Recommended)

  • Monocryl (poliglecaprone 25): Retains 20-30% breaking strength at 2 weeks; complete absorption between 91-119 days 2
  • Maxon (polyglyconate): Half-life tensile strength of 3 weeks; complete absorption between 90-110 days 5, 4
  • PDS II (polydioxanone): Half-life tensile strength of 6 weeks; maintains elastic properties longer despite degradation 3, 4

Clinical Significance of Absorption Timeline

The critical wound healing period is 2-4 weeks, during which slowly absorbable sutures maintain adequate tensile strength before beginning significant degradation. 1, 6, 2

Strength Retention During Critical Period

  • Slowly absorbable monofilaments (Maxon, PDS II) sustain the highest loads between days 14-28 (171-182 N) 3
  • This extended strength retention explains why slowly absorbable sutures demonstrate lower incisional hernia rates compared to rapidly absorbable options 7, 1

Complete Absorption Window

  • Most slowly absorbable sutures: 90-119 days 2, 5
  • Tissue reaction during absorption is typically slight to minimal 2

Common Pitfalls to Avoid

Do not use rapidly absorbable sutures for fascial or deep tissue closure, as they lose critical tensile strength before adequate wound healing occurs, increasing incisional hernia risk. 7, 1

  • Rapidly absorbable sutures are not recommended for midline laparotomy closures based on high-quality evidence with 99.2% expert agreement 7
  • The premature loss of tensile strength (within 2-6 weeks) occurs before complete wound maturation 3, 4

References

Guideline

Optimal Suture Selection for Buried Applications

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

In-vivo comparison of four absorbable sutures: Vicryl, Dexon Plus, Maxon and PDS.

Canadian journal of surgery. Journal canadien de chirurgie, 1988

Research

Scientific basis for the selection of skin closure techniques.

Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer, 2010

Guideline

Suture Material Recommendations for Foot Surgery

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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