When is a Fetal Pole Seen on Ultrasound?
Direct Answer
The embryo (not "fetal pole") is typically visible on transvaginal ultrasound at approximately 6 weeks gestational age. 1, 2
Important Terminology Update
The term "fetal pole" is obsolete and should be avoided in modern practice. 3 The correct terminology is:
- "Embryo" for conceptus ≤10 weeks 6 days gestational age 3, 1
- "Fetus" beginning at 11 weeks 0 days gestational age 3, 1
Sequential Timeline of Early Pregnancy Visualization
The structures appear in this order on transvaginal ultrasound:
5 Weeks Gestational Age
- Gestational sac is the earliest finding, appearing as a round or oval fluid collection with a hyperechoic rim 3, 1, 2
- Gestational sacs as small as 2-3 mm in mean sac diameter may be visible 2
5½ Weeks Gestational Age
- Yolk sac becomes visible as a thin-rimmed circular structure 3, 1
- The presence of a yolk sac provides incontrovertible evidence of pregnancy 1, 2
6 Weeks Gestational Age
- Embryo with cardiac activity is typically visualized 1, 2
- Research confirms the embryo and cardiac activity can be detected as early as 34 days from last menstrual period with transvaginal ultrasound 4
- Cardiac activity is detectable in embryos with crown-rump length ≥3 mm 4
7 Weeks Gestational Age
Clinical Measurement Guidelines
Once an embryo is measurable, crown-rump length (CRL) should be used for dating, as it is more accurate than mean sac diameter. 3, 1
Critical Pitfalls to Avoid
Timing Considerations
- No ultrasound can visualize pregnancy at 2 weeks gestational age because conception has not yet occurred (ovulation occurs at 2 weeks GA) 2
- The earliest clinically useful transvaginal ultrasound should be performed at approximately 5 weeks gestational age or later 2
Diagnostic Criteria for Pregnancy Failure
- Absence of embryo in gestational sac >16 mm indicates poor prognosis 1
- Absence of cardiac activity in embryo ≥7 mm CRL is definitive for embryonic demise 1, 2
- For embryos <7 mm CRL without cardiac activity, follow-up ultrasound in 7-10 days is recommended 1, 2
- An "empty amnion" (visible amnion without embryo) is always associated with pregnancy loss 5
Reporting Standards
- Before visualizing yolk sac or embryo, report as "probable gestational sac" or "probable pregnancy" 3, 1
- With yolk sac present, report as "definite gestational sac" or "definite pregnancy" 3, 1
- Report cardiac activity as "cardiac activity" or "cardiac motion", avoiding terms like "heartbeat" or "heart motion" 1, 2
Correlation with hCG Levels
A gestational sac should be visible when hCG reaches approximately 1000-2000 mIU/mL, though levels up to 3000 mIU/mL may be needed to reliably exclude normal intrauterine pregnancy. 2