Is high SHBG causing low free testosterone the likely cause of erectile dysfunction or is it more related to psychological factors?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board

Educational purpose only • Exercise caution as content is pending human review

Article Review Status

Submitted

Under Review

Approved

Last updated: December 30, 2025 • View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Related Questions

Could my recent low libido and erectile dysfunction be due to elevated sex hormone‑binding globulin causing low free testosterone despite a total testosterone of ~40 nmol/L, and what evaluation and treatment should I pursue?

What is the management approach for a patient with low Sex Hormone-Binding Globulin (SHBG) and hypogonadism?

Is high SHBG and low free Testosterone a likely cause of semen changes, low libido, Erectile Dysfunction, and testicular atrophy?

I am a male with one year of low libido and new erectile dysfunction (previously high libido); labs show total testosterone 40 nmol/L (normal‑high), SHBG 95 nmol/L (elevated), LH 7.2 IU/L (upper normal), FSH 9.9 IU/L (normal), semen analysis 45 million/mL—why are these findings causing my symptoms and what is the appropriate management?

What is the difference between free and total testosterone in middle-aged to older males with potential hypogonadism?

What is the appropriate management for unilateral cervical lymph node swelling?

What are the signs and symptoms of ABO (Blood Type) incompatibility?

How to manage a patient with a class 1 food allergy and Crohn's disease, considering serum IgE (Immunoglobulin E) levels?

Is Azithromycin (a macrolide antibiotic) a suitable treatment for Pelvic Inflammatory Disease (PID)?

What initial evaluation and management are required for a 60-year-old female patient with a history of Chronic Obstructive Pulmonary Disease (COPD), osteoarthritis, hyperlipidemia, Gastroesophageal Reflux Disease (GERD), Sjogren's syndrome, rheumatoid arthritis, and chronic depression who has fallen and hit her head and knee?

What is the cause of elevated hemoglobin, hematocrit, and iron levels in a male?

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.