From the Guidelines
Bromfed is a combination medication containing brompheniramine and pseudoephedrine, used to treat symptoms of the common cold, allergies, and upper respiratory infections, with a recommended adult dosage of one tablet or 5-10 mL of liquid every 4-6 hours, not exceeding 4 doses in 24 hours 1.
Key Points
- Bromfed works by blocking histamine receptors to reduce allergy symptoms like sneezing and runny nose, while also constricting blood vessels in the nasal passages to relieve congestion.
- Common side effects include drowsiness, dry mouth, dizziness, and nervousness.
- Bromfed should be used with caution in people with high blood pressure, heart disease, diabetes, thyroid disorders, or glaucoma.
- It may interact with MAO inhibitors, other antihistamines, and certain antidepressants.
- According to the study published in the Journal of Allergy and Clinical Immunology 1, the use of OTC cough and cold medications, including bromfed, should be avoided in children under 6 years of age due to potential toxicity and lack of efficacy.
Important Considerations
- The FDA’s Nonprescription Drugs and Pediatric Advisory Committees have recommended that OTC medications used to treat cough and cold no longer be used for children below 6 years of age 1.
- Second-generation antihistamines, such as cetirizine and loratadine, have been shown to be well tolerated and have a good safety profile in young children 1.
- Bromfed is available by prescription only and should be taken exactly as directed by a healthcare provider.
From the FDA Drug Label
Bromfed® DM Cough Syrup is a clear, light pink syrup with a butterscotch flavor. Each 5 mL (1 teaspoonful) contains: Brompheniramine Maleate, USP . . . . . . . . 2 mg Pseudoephedrine Hydrochloride, USP . . . . . 30 mg Dextromethorphan Hydrobromide, USP . . . 10 mg Antihistamine/Nasal Decongestant/Antitussive syrup for oral administration.
Bromfed is an Antihistamine/Nasal Decongestant/Antitussive syrup that contains Brompheniramine Maleate, Pseudoephedrine Hydrochloride, and Dextromethorphan Hydrobromide for oral administration 2.
- Key ingredients:
- Brompheniramine Maleate: 2 mg
- Pseudoephedrine Hydrochloride: 30 mg
- Dextromethorphan Hydrobromide: 10 mg
- Indication: Oral administration as a cough syrup.
From the Research
Definition of Bromfed
- Bromfed is not defined in the provided studies 3, 4, 5, 6.
- The studies focus on monoamine oxidase inhibitors (MAOIs) and their use in treating depression and other conditions.
- There is no mention of Bromfed in the texts, suggesting that it may not be related to the topic of MAOIs or the treatment of depression.
Possible Relation to MAOIs
- Without further information, it is unclear if Bromfed is related to MAOIs or if it has any interaction with these types of medications.
- The studies provide information on the use of MAOIs, their mechanisms of action, and potential interactions with other medications, but do not mention Bromfed specifically 3, 4, 5, 6.
- Further research would be needed to determine if Bromfed has any connection to MAOIs or if it is used in the treatment of depression or other conditions.