Immediate Triage of a Red Patient in Multiple Car Crash
In a multiple car crash with a critically injured "red" patient (immediate/life-threatening category), prioritize exsanguinating hemorrhage control FIRST before airway management, followed by immediate surgical/interventional bleeding control, unless there is imminent cerebral herniation or critical airway obstruction. 1, 2
Primary Survey: Circulation-First Approach (x-ABC)
The traditional ABC sequence has been superseded by the x-ABC approach where "x" represents exsanguinating hemorrhage control, which must be addressed before airway management in patients with severe bleeding 1, 2.
Step 1: Immediate Hemorrhage Control (The "X")
- Apply direct manual compression to any visible external bleeding sites immediately 3
- Apply tourniquet to extremity hemorrhage if direct compression fails - tourniquets should remain in place until surgical control is achieved, with maximum safe application time of 2-6 hours 3
- Apply pelvic binder immediately if pelvic fracture is suspected based on mechanism (high-energy deceleration, motor vehicle crash) - this reduces pelvic volume and tamponades venous bleeding 4
Critical Evidence: Recent prospective data demonstrates that prehospital circulation-first prioritization (x-ABC) reduces in-hospital mortality from 47% to 13% (p<0.001) in patients with severe hemorrhage and SBP <90 mmHg 2. Delaying intubation to prioritize circulation avoids post-intubation hypotension, which increases mortality from 19.6% to 33.2% 5.
Step 2: Rapid Hemorrhage Assessment
Classify shock severity using vital signs and response to resuscitation 3:
- Class III-IV Shock (>30% blood loss): HR >120, SBP decreased, altered mental status, urine output <15 mL/h
- Mechanism of injury: High-energy deceleration, falls >6 meters, penetrating trauma indicate high bleeding risk 3
- FAST examination: Perform immediately to identify intra-abdominal free fluid 3, 4
Step 3: Initiate Massive Transfusion Protocol
- Start balanced blood product resuscitation with 1:1:1 ratio of packed RBCs:FFP:platelets immediately 4
- Target permissive hypotension: SBP 80-100 mmHg until hemorrhage control achieved 4
- Avoid excessive crystalloid - this worsens coagulopathy and dilutional effects 3, 6
Airway Management: When and How
Delay advanced airway management if the patient has severe hemorrhage (Class III-IV shock) and no critical airway obstruction or imminent herniation 1, 5, 2.
Indications to Proceed with Immediate Intubation Despite Bleeding:
- Imminent cerebral herniation signs (unilateral pupil dilation, posturing) 3
- Critical airway obstruction that cannot be managed with basic maneuvers 3
- Severe hypoxia (SpO2 <90%) refractory to supplemental oxygen 3
- GCS ≤8 with inability to protect airway 3
If Intubation is Required:
- Maintain normoventilation (EtCO2 35-40 mmHg) - avoid hyperventilation which causes cerebral vasoconstriction and worsens outcomes 3
- Monitor EtCO2 continuously to confirm tube placement and maintain appropriate ventilation 3
- Use low tidal volumes (6-8 mL/kg) with moderate PEEP to prevent ventilator-induced lung injury 3
- Prepare for post-intubation hypotension with blood products ready and vasopressors available 5
Definitive Bleeding Control Algorithm
For Pelvic Fracture with Hemodynamic Instability:
Decision Point: FAST Examination Result 4
- FAST negative (no intra-abdominal fluid): Proceed directly to angiographic embolization - this has 87% success rate for controlling pelvic bleeding 4
- FAST positive (significant free fluid): Proceed to emergency laparotomy for intra-abdominal source control, followed by pelvic embolization if needed 4
Critical Pitfall: Never perform laparotomy for isolated pelvic bleeding - it does not control retroperitoneal hemorrhage and worsens hemodynamics 4
For Abdominal Hemorrhage:
- Hypotensive patient (SBP <90 mmHg) with positive FAST: Immediate laparotomy 3
- Transient responders to resuscitation: Candidates for immediate surgical bleeding control 3
- Non-responders to initial fluid resuscitation: Immediate operative intervention required 3
For Extremity Hemorrhage:
- Direct compression as first-line 3
- Tourniquet application if compression fails - do not rely on "pressure point control" which is ineffective 3
Spinal Precautions During Resuscitation
Maintain spinal immobilization throughout resuscitation but do not allow spinal precautions to delay life-saving hemorrhage control interventions 3. Manual in-line stabilization during airway management if intubation is required 3.
Imaging Decisions
Hemodynamically Unstable Patients:
- FAST only - do not transport to CT scanner 3, 4
- Proceed directly to operating room or interventional radiology based on FAST results 3, 4
Hemodynamically Stable Patients:
- Whole-body CT can be performed if patient remains stable with SBP >90 mmHg 3
- CT reduces time to definitive diagnosis (12±9 minutes vs 41±27 minutes with conventional workup) 3
Common Pitfalls to Avoid
- Never delay hemorrhage control for airway management in exsanguinating patients without critical airway compromise 1, 2
- Never hyperventilate trauma patients - this increases mortality through cerebral vasoconstriction and decreased venous return 3
- Never transport unstable patients to CT - use FAST and proceed to definitive intervention 3, 4
- Never perform laparotomy for isolated pelvic bleeding - use angioembolization 4
- Never rely on continued resuscitation without source control - this creates a vicious cycle of coagulopathy 4