What ointment is recommended for a first-degree burn?

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Last updated: December 31, 2025View editorial policy

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First-Degree Burn Ointment Recommendation

For first-degree burns, apply petrolatum or petrolatum-based antibiotic ointment (such as triple antibiotic ointment containing bacitracin, neomycin sulfate, and polymyxin B) after cooling the burn with clean running water for 5-20 minutes. 1, 2

Immediate First Steps (Before Ointment Application)

  • Cool the burn immediately with clean running water for 5-20 minutes to limit tissue damage and reduce pain 1, 2
  • Remove any jewelry from the affected area before swelling occurs to prevent vascular compromise 1
  • Clean the wound with tap water, isotonic saline, or antiseptic solution 1
  • Administer over-the-counter analgesics such as acetaminophen or NSAIDs for pain control 1, 3

Recommended Topical Agents for First-Degree Burns

Primary recommendation:

  • Petrolatum or petrolatum-based antibiotic ointment is the first-line treatment, promoting faster reepithelialization and reduced scar formation 1, 2
  • Triple antibiotic ointment (containing bacitracin, neomycin sulfate, and polymyxin B) is specifically recommended 1, 3

Alternative options for home management:

  • Honey shows benefit for infection resolution and reduced hypertrophic scarring 2
  • Aloe vera may be reasonable for small burns being managed at home 1, 2

Application Protocol

  • Apply a thin layer of petrolatum or petrolatum-based antibiotic ointment to the burn wound 2
  • Cover with a clean, non-adherent dressing 1, 2
  • Change dressing daily or as needed 2
  • Monitor for signs of infection including increased pain, redness, swelling, or discharge 1

Critical Pitfalls to Avoid

  • DO NOT apply ice directly to burns, as it causes additional tissue damage 1, 2, 3
  • DO NOT apply butter, oil, or other home remedies to burns, as these can exacerbate injury 1, 2, 3
  • DO NOT use silver sulfadiazine as first-line therapy, as it delays healing and worsens scarring compared to petrolatum-based treatments 2, 3
  • DO NOT break intact blisters, as this significantly increases infection risk 2, 3

When to Seek Medical Attention

  • Burns involving the face, hands, feet, or genitals require specialized evaluation regardless of size 1, 2, 3
  • Signs of inhalation injury (soot around nose/mouth, difficulty breathing) require immediate medical attention 1, 3
  • Burns covering >10% body surface area in adults require specialized burn center care 3

References

Guideline

Management of Scalds and Burns

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Management of Open Partial-Thickness Burns

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Management of Second-Degree Burns

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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