What is the cause of left flank pain that worsens with lifting of the leg?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: April 10, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Differential Diagnosis for Left Flank Pain with Pain when Lifting Leg

  • Single Most Likely Diagnosis
    • Musculoskeletal strain: This is the most likely diagnosis given the symptoms. Lifting a leg can exacerbate musculoskeletal issues in the lower back or flank area, leading to pain.
  • Other Likely Diagnoses
    • Nephrolithiasis (kidney stones): Pain from kidney stones can be exacerbated by movement, including lifting a leg, and is often felt in the flank.
    • Pyelonephritis: An infection of the kidney can cause flank pain that may worsen with movement or lifting.
    • Herniated disk: A herniated disk in the lower spine can cause pain in the flank area, especially when lifting or bending.
  • Do Not Miss Diagnoses
    • Appendicitis (if pain radiates to the right side or is accompanied by other symptoms like fever, nausea): Although appendicitis typically presents with right lower quadrant pain, atypical presentations can occur, and missing this diagnosis can be serious.
    • Aortic dissection or aneurysm: Severe, tearing pain in the flank that worsens with movement could indicate an aortic emergency, which is life-threatening and requires immediate attention.
    • Pulmonary embolism (if accompanied by respiratory symptoms): While less common, pulmonary embolism can cause flank pain if the embolism affects the upper parts of the lung, and it is crucial not to miss this potentially fatal condition.
  • Rare Diagnoses
    • Psoas abscess: A collection of pus in the psoas muscle can cause flank pain that worsens with movement, including lifting a leg.
    • Retroperitoneal fibrosis: A rare condition characterized by the proliferation of fibrous tissue in the retroperitoneum, which can cause flank pain and other symptoms.
    • Eosinophilic granuloma (part of Langerhans cell histiocytosis): A rare condition that can affect various parts of the body, including the bones, and cause pain in the affected area.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.