What could be causing my persistent nasal and ear pressure symptoms despite clear CTA, MRI, and CT scans of my sinuses?

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Persistent Nasal and Ear Pressure with Normal Imaging: Likely Chronic Rhinosinusitis or Eustachian Tube Dysfunction

Your symptoms—persistent nasal/facial pressure, ear fullness requiring constant popping, and 24/7 symptoms for two years—strongly suggest chronic rhinosinusitis (CRS) or eustachian tube dysfunction, even with normal CT scans, and you should undergo nasal endoscopy for direct visualization and consider a trial of intranasal corticosteroids before any further imaging. 1, 2

Why Your Scans May Be Normal Despite Real Symptoms

  • CT scans have significant limitations: Up to 35% of patients with true CRS have normal endoscopic findings, and imaging alone cannot capture all inflammatory changes, particularly early mucosal inflammation or functional obstruction. 2

  • Symptoms alone have poor correlation with imaging: Clinical criteria for sinusitis have only 37-73% sensitivity, meaning many patients with genuine disease have minimal or no radiographic findings. 2

  • Your symptom pattern fits CRS criteria: The European Position Paper on Rhinosinusitis (EPOS) defines CRS as ≥2 cardinal symptoms (nasal blockage, discharge, facial pressure/pain, smell reduction) persisting ≥12 weeks—you clearly meet this with two years of continuous facial/nasal pressure and ear symptoms. 2

What You Actually Need Now

Mandatory Next Step: Nasal Endoscopy

  • Direct visualization is essential: The American Academy of Otolaryngology states that symptoms alone are insufficient for diagnosis and objective documentation of inflammation through nasal endoscopy is required. 2

  • Endoscopy sees what CT misses: It provides superior visualization of the posterior nasal cavity, nasopharynx, sinus drainage pathways (ostiomeatal complex), and can identify subtle mucosal inflammation, polyps, or anatomic variants causing functional obstruction. 2

  • Anterior rhinoscopy is inadequate: Simple office examination through the nostrils has low sensitivity and specificity and cannot adequately assess the areas relevant to your symptoms. 2

Immediate Treatment Trial

  • Start intranasal corticosteroids immediately: The EPOS guidelines recommend fluticasone propionate 2 sprays per nostril once daily for the first week, then 1-2 sprays per nostril once daily, as this is the most effective single agent for nasal congestion and pressure symptoms in CRS. 2

  • Alternative regimen: Mometasone furoate 200 μg twice daily showed significant improvement in nasal obstruction and rhinorrhea at 4 months in multiple trials. 2

Addressing Your Ear Pressure

  • Eustachian tube dysfunction is likely secondary: Your constant ear pressure and need to pop your ears suggests eustachian tube dysfunction, which commonly accompanies chronic nasal/sinus inflammation due to shared mucosal lining and drainage pathways. 1

  • The connection: Chronic inflammation in the nasopharynx and posterior nasal cavity (where the eustachian tube openings are located) causes functional obstruction even without visible structural abnormalities on CT. 1

Critical Pitfalls You've Already Encountered

  • Over-reliance on imaging: The American Academy of Otolaryngology explicitly states that radiographic imaging is unnecessary for diagnosis when clinical criteria are met, and CT cannot distinguish between different types of rhinosinusitis based on imaging alone. 1, 3

  • Multiple CT scans without endoscopy: You've had "several CT scans" but apparently no nasal endoscopy—this is backwards, as endoscopy should precede advanced imaging in most cases. 2

  • No trial of appropriate medical therapy: There's no mention you've tried intranasal corticosteroids, which are first-line treatment and can be both diagnostic and therapeutic. 2

What Could Be Missed on Standard Workup

Consider These Specific Conditions:

  • Chronic hyperplastic eosinophilic rhinosinusitis: This non-infectious form doesn't respond to antibiotics, is marked by eosinophils rather than neutrophils, and may require systemic corticosteroids—it can present with normal or minimal CT findings. 1

  • Allergic rhinitis as underlying cause: Up to 60% of patients with recurrent or difficult-to-treat CRS have significant allergic sensitivities to perennial allergens, which can cause chronic inflammation without dramatic CT changes. 2

  • Anatomic variants causing functional obstruction: Septal deviation compressing the middle turbinate, concha bullosa (air-filled turbinate), or other variants can cause symptoms without obvious "disease" on CT. 1

Additional Workup to Request:

  • Allergy testing: Given your persistent symptoms, testing for environmental allergens is warranted as allergic rhinitis commonly leads to secondary sinusitis. 1, 2

  • Consider immunodeficiency evaluation if symptoms persist: Particularly if you have history of recurrent infections elsewhere (otitis media, bronchitis, pneumonia), measurement of quantitative immunoglobulins (IgG, IgA, IgM) and specific antibody responses should be considered. 1

What NOT to Do

  • No more CT scans without endoscopy first: Additional imaging without direct visualization and medical treatment trial is not indicated and exposes you to unnecessary radiation. 1, 3

  • Avoid surgical procedures without medical optimization: Any sinus surgery, septoplasty, or turbinate reduction should only be considered after aggressive medical management has failed and endoscopy confirms specific structural problems. 1, 2

  • Don't accept "nothing is wrong": Normal imaging does not equal no disease—your symptoms are real and warrant proper evaluation with endoscopy and treatment trial. 2

Specific Action Plan

  1. Request nasal endoscopy from an otolaryngologist (not just anterior rhinoscopy in primary care). 2

  2. Start intranasal corticosteroid spray (fluticasone or mometasone) as described above while awaiting endoscopy. 2

  3. Get allergy testing to identify potential triggers. 2

  4. If endoscopy shows inflammation, continue medical therapy for at least 8-12 weeks before considering any surgical intervention. 1, 2

  5. If symptoms persist despite optimal medical therapy and endoscopy, then repeat CT may be warranted specifically for surgical planning—but only after these steps. 2

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Diagnostic Criteria for Chronic Rhinosinusitis

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

CT Scan of the Sinuses is Not Medically Necessary for Chronic Halitosis and Postnasal Drip

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

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Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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