Indications for RFA and Epidural Steroids in Back Pain
The 2025 BMJ guideline strongly recommends AGAINST both radiofrequency ablation and epidural steroid injections for chronic axial (non-radicular) spine pain in adults, regardless of age or degenerative findings like spondylosis, degenerative disc disease, or facet osteoarthritis. 1
Critical Distinction: Axial vs. Radicular Pain
The type of back pain fundamentally determines appropriateness of these interventions:
For Chronic Axial (Non-Radicular) Back Pain
- Strong recommendation AGAINST epidural steroids for pure axial low back pain without radicular symptoms 1
- Strong recommendation AGAINST radiofrequency ablation for chronic axial spine pain 1
- This applies even when imaging shows lumbar spondylosis, degenerative disc disease, or facet joint osteoarthritis 1
- The 2020 NICE guideline explicitly states: "Do not offer spinal injections for managing low back pain" 1
For Chronic Radicular Pain (Sciatica with Leg Symptoms)
Epidural steroid injections may be considered when:
- Disc herniation/bulge causes radicular leg pain 1, 2
- Spinal stenosis produces radiculopathy 1
- Post-surgical syndrome with radicular symptoms 1
- Significant leg pain predominates over back pain 1
The 2022 American Society of Pain and Neuroscience provides strong support for epidural injections (interlaminar, transforaminal, or caudal) specifically for radicular pain from these conditions 1
Specific Scenarios Where RFA May Be Considered
Radiofrequency ablation should ONLY be performed after:
Positive diagnostic medial branch block showing >50-80% pain relief 1
- Note: Diagnostic blocks carry false positive rates up to 60% 1
Failed conservative treatment including physical therapy and medications 1
Suspected facet-mediated pain with specific clinical features:
The 2020 NICE guideline states: "Only perform radiofrequency denervation for chronic low back pain after a positive response to a medial branch block" 1
Sacroiliac Joint Pain Exception
RFA for sacroiliac joint dysfunction receives stronger support:
- Strong recommendation for SI joint denervation/ablation after failed conservative treatment 1
- Consider after failed SI joint intraarticular steroid injection 1
- Requires positive diagnostic SI joint injection 1
Key Clinical Pitfalls
Common errors to avoid:
Do not offer these procedures based solely on imaging findings (spondylosis, disc degeneration, facet arthritis on MRI/CT) without appropriate pain pattern 1
Do not bypass diagnostic blocks before RFA - the false positive rate makes clinical diagnosis alone unreliable 1
Do not confuse radicular with axial pain - epidural steroids are contraindicated for pure axial pain but may help radiculopathy 1, 2
Recognize limited durability - even when appropriate, RFA typically provides 3-6 months relief requiring repeat procedures 1, 4
Harm Considerations
These procedures carry non-trivial risks:
- Prolonged pain/stiffness (8.6%) 4
- Temporary altered consciousness (2.1%) 4
- Dural puncture (1.4%) 4
- Deep infection (0.7%) 4
- Rare catastrophic complications including paralysis and death 1, 4
Evidence Quality Context
The 2025 BMJ guideline analyzed 81 randomized trials (7,977 patients) and found interventional procedures provide minimal benefit for axial pain, with median baseline pain of 6.8/10 and median pain duration of 46 months 1. The strong recommendation against these procedures reflects that harms and costs outweigh minimal benefits for non-radicular pain 1.