Treatment of Painful Hemorrhoids
For painful hemorrhoids, initiate conservative management with increased fiber (25-30g daily) and water intake, combined with topical 0.3% nifedipine plus 1.5% lidocaine ointment applied every 12 hours for two weeks, which achieves 92% resolution rates. 1
Initial Assessment
Before treating, determine the hemorrhoid type and timing:
- Internal hemorrhoids (above dentate line) typically cause painless bleeding and prolapse, not acute pain 2
- External hemorrhoids (below dentate line) cause pain only when thrombosed 1, 2
- Thrombosed external hemorrhoids present with acute-onset anal pain and palpable perianal lump 3
- Perform anoscopy when feasible to confirm diagnosis and rule out other anorectal pathology 4, 3
Critical pitfall: Anal pain is generally NOT associated with uncomplicated internal hemorrhoids—its presence suggests thrombosis, fissure, or abscess. 1
First-Line Conservative Management (All Painful Hemorrhoids)
This is a strong recommendation and should be initiated immediately: 4
- Increase dietary fiber to 25-30g daily (can use psyllium husk 5-6 teaspoonfuls with 600mL water daily) 4, 1
- Increase water intake to soften stool and reduce straining 4, 3
- Avoid straining during defecation 1
- Warm sitz baths to reduce inflammation and discomfort 1
Pharmacological Management
For Thrombosed External Hemorrhoids (Most Common Cause of Pain)
Timing determines treatment approach:
Presentation Within 72 Hours
- Surgical excision under local anesthesia is preferred, providing faster pain relief and lower recurrence rates 1, 3, 2
- This can be performed as an outpatient procedure 3
- Never perform simple incision and drainage—this leads to persistent bleeding and higher recurrence 4, 1, 3
Presentation Beyond 72 Hours
Conservative management is preferred as natural resolution has begun: 1, 3
- Topical 0.3% nifedipine with 1.5% lidocaine ointment applied every 12 hours for two weeks (92% resolution rate vs 45.8% with lidocaine alone) 1, 3
- This works by relaxing internal anal sphincter hypertonicity without systemic side effects 1
- Oral analgesics (acetaminophen or ibuprofen) for additional pain control 1
- Flavonoids (phlebotonics) to relieve bleeding, pain, and swelling (though 80% symptom recurrence within 3-6 months after cessation) 4, 1, 2
Additional Topical Options
- Topical lidocaine 1.5-2% ointment or cream for symptomatic pain relief 1, 3
- Topical muscle relaxants for additional pain relief, particularly with severe sphincter spasm 4, 1, 3
- Short-term topical corticosteroids (≤7 days maximum) to reduce local inflammation 1, 3
Alternative Topical Agents (Less Preferred)
- Topical nitrates show good results but limited by high incidence of headache (up to 50%) 1
- Topical heparin significantly improves healing, though evidence limited to small studies 1
When Conservative Management Fails
If symptoms worsen or fail to improve within 1-2 weeks: 1, 3
For Internal Hemorrhoids (Grades I-III)
- Rubber band ligation is first-line procedural treatment (70.5-89% success rate) 1, 2, 5
- More effective than sclerotherapy or infrared photocoagulation 1
For Grade III-IV or Mixed Hemorrhoids
- Excisional hemorrhoidectomy provides definitive treatment with lowest recurrence (2-10%) 1, 2, 5
- Reserved for failure of medical and office-based therapy 1
Critical Pitfalls to Avoid
- Never attribute significant bleeding or anemia to hemorrhoids without colonoscopy to rule out inflammatory bowel disease or colorectal cancer 4, 1
- Never use corticosteroid creams >7 days—causes tissue thinning and increased injury risk 4, 1, 3
- Never perform incision and drainage alone for thrombosed hemorrhoids—leads to persistent bleeding and recurrence 4, 1, 3
- Never assume all anorectal pain is from hemorrhoids—anal fissures coexist in up to 20% of patients 1
- Severe pain with fever and urinary retention suggests necrotizing pelvic sepsis requiring emergency evaluation 1