Uremol HC Dosing
Uremol HC is dosed as one tablet orally 4 times per day, followed by liberal fluid intake in adults. 1
Adult Dosing
- Standard dose: 1 tablet orally 4 times daily 1
- Must be followed by liberal fluid intake to ensure adequate hydration 1
Pediatric Dosing
- Dosage must be individualized by a physician for older children 1
- Not recommended for children 6 years of age or younger 1
Important Clarification
The evidence provided appears to contain a labeling discrepancy. The user question asks about "Uremol HC" with context suggesting sodium polystyrene sulfonate (Kayexalate) for hyperkalemia, but the FDA label 1 describes "Urelle®," which is actually a urinary analgesic/antiseptic combination product, not a potassium binder. These are completely different medications with different indications.
If the question is actually about sodium polystyrene sulfonate (Kayexalate) for hyperkalemia:
Kayexalate Dosing for Hyperkalemia
- Oral: 15-30 g orally, typically given 1-4 times daily 2, 3, 4
- Rectal: 30-50 g as retention enema 2
- The practical exchange ratio is approximately 1 mEq potassium per 1 gram of resin 2
- Studies show 30 g daily can reduce serum potassium by 1.04 mEq/L more than placebo over 7 days 2, 4
Critical Safety Warnings for Kayexalate
- Should NOT be used as emergency treatment for life-threatening hyperkalemia due to delayed onset of action 2
- Concomitant administration with sorbitol is not recommended due to risk of intestinal necrosis 2
- Serious gastrointestinal adverse events including intestinal necrosis have been reported 2
- Contains 100 mg (4.3 mmol) sodium per 100 g powder, which may be problematic in patients with hypertension or fluid overload 2