From the Research
Topical tranexamic acid should be incorporated into your skincare routine once or twice daily, typically as a serum applied after cleansing and before moisturizing, starting with a product containing 2-5% tranexamic acid, as evidenced by the most recent study in 2023 1. When using topical tranexamic acid, it is essential to apply a pea-sized amount to clean, dry skin, focusing on areas with hyperpigmentation or melasma. Allow it to absorb for a few minutes before applying other products. For best results, use consistently for at least 8-12 weeks, as visible improvements take time. Some key points to consider when incorporating topical tranexamic acid into your skincare routine include:
- Always apply sunscreen (SPF 30+) during the day when using tranexamic acid, as sun exposure can worsen pigmentation issues, as noted in various studies 2, 3, 4.
- If you're using other active ingredients like retinoids or vitamin C, consider using tranexamic acid in the morning and these other actives at night to minimize potential irritation.
- Tranexamic acid works by inhibiting plasmin activity, which reduces melanin production and helps fade dark spots and even skin tone.
- Those with sensitive skin should start with lower concentrations and gradually increase usage to avoid potential irritation, as suggested by the review of tranexamic acid uses in dermatology 5. It is also worth noting that combination therapy with vitamin C may be beneficial, as shown in a pilot study in 2023 1, which demonstrated the efficacy of topical tranexamic acid 2% combined with vitamin C 2% in treating refractory melasma.