Management of Incomplete Abortion
For incomplete abortion, surgical evacuation with vacuum aspiration is the preferred treatment due to superior safety profile, with significantly lower rates of hemorrhage (9.1% vs 28.3%), infection (1.3% vs 23.9%), and retained tissue requiring additional procedures (1.3% vs 17.4%) compared to medical management. 1
Initial Assessment and Stabilization
Immediate Evaluation
- Confirm diagnosis with transvaginal ultrasound showing intracavitary tissue with internal vascularity, persistent gestational sac, or thickened endometrium with retained products 2
- Assess hemodynamic stability: obtain vital signs, complete blood count, coagulation parameters, blood typing and cross-matching if profuse bleeding present 1
- Rule out infection by checking for maternal tachycardia, purulent cervical discharge, uterine tenderness, or fever—though fever may be absent in early infection 1
- Determine Rh status immediately 2
Critical Red Flags Requiring Urgent Intervention
- Profuse vaginal bleeding: Transfuse packed red blood cells if hemoglobin <7 g/dL or signs of ongoing hemorrhage 1
- Signs of infection: Initiate broad-spectrum antibiotics immediately and proceed with urgent surgical evacuation without waiting for fever or laboratory confirmation 1
- Hemodynamic instability: These patients are absolute contraindications to medical management 2
Treatment Options
Surgical Management (Preferred)
Vacuum aspiration is the procedure of choice for incomplete abortion at any gestational age up to 12 weeks 2, 3
Advantages of Surgical Evacuation:
- Less blood loss (17 mL less than sharp curettage) 3
- Less pain (RR 0.74,95% CI 0.61-0.90) 3
- Shorter procedure duration (1.2 minutes faster) 3
- Lower infection risk (1.3% vs 23.9% with medical) 1
- Lower hemorrhage risk (9.1% vs 28.3% with medical) 1
- Immediate resolution with 100% success rate 1
Technique:
- Use vacuum aspiration rather than sharp curettage to minimize complications 3
- Provide appropriate analgesia and sedation 3
- Perform as outpatient/day case procedure 1
Medical Management (Alternative)
Medical management with misoprostol is acceptable only when all of the following criteria are met 2:
- Gestational age ≤12 weeks 2
- Hemodynamically stable 2
- No signs of infection 2
- Patient preference for non-surgical approach 1
Dosing Regimen:
- Misoprostol 600 mcg orally as single dose (91.5% success rate) 2, 4
- Alternative: 400 mcg sublingual (94.4% success rate) 5
- May require second dose if incomplete after one week 4
Expected Side Effects:
- Longer duration of bleeding compared to surgical 4
- Greater need for analgesia 4
- Fever, shivering, and cramping common 6
Follow-up Protocol:
- Return in one week to confirm complete evacuation 5
- If still incomplete, offer immediate surgical evacuation 5
Adjunctive Therapy for Incomplete Abortion
Oxytocin may be used as adjunctive therapy in first trimester incomplete abortion, though curettage is generally considered primary therapy 7
Oxytocin Dosing (if used):
- Add 10 units oxytocin to 500 mL physiologic saline or 5% dextrose in saline 7
- Infuse at 20-40 drops/minute 7
Essential Prophylaxis
Rh Immunoglobulin Administration
All Rh-negative women with incomplete abortion MUST receive anti-D immunoglobulin 2, 1
- Dose: 50 mcg (or 50 μg) for incomplete or complete abortion 1, 2
- Administer immediately—do not delay 2
- Fetomaternal hemorrhage occurs in 22-32% of spontaneous abortions 2, 1
- Failure to provide prophylaxis causes alloimmunization affecting future pregnancies 2
Post-Treatment Care
Immediate Contraceptive Counseling
Provide contraceptive counseling immediately as ovulation resumes within 2-4 weeks post-abortion 1, 2
- Combined hormonal contraceptives or implants can be initiated immediately after complete abortion 1, 2
- If starting within 7 days of abortion: no backup contraception needed 1, 2
- If starting after 5 days from menstrual bleeding: backup contraception required for 7 days 2
Follow-up
- Confirm complete resolution clinically 1
- Monitor for complications including infection, hemorrhage, or retained tissue 1
Common Pitfalls to Avoid
Delaying treatment while waiting for fever in suspected infection: Clinical signs (tachycardia, purulent discharge, uterine tenderness) warrant immediate antibiotics and evacuation 1
Using sharp curettage instead of vacuum aspiration: Vacuum aspiration has superior safety profile with less blood loss, pain, and shorter duration 3
Offering medical management beyond 12 weeks or with contraindications: This significantly increases failure rates and complications 2
Forgetting Rh immunoglobulin: This critical step prevents alloimmunization in 22-32% of cases at risk 2, 1
Inadequate contraceptive counseling: Ovulation returns rapidly, risking unintended pregnancy 1, 2