What is the medical term for body weakness?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: January 9, 2026View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Medical Terminology for Body Weakness

The medical term for body weakness is "asthenia," which derives from Greek meaning "absence of strength or vigor." 1

Definition and Clinical Context

Asthenia is the formal medical term used to describe a subjective feeling of weakness, lack of energy, or absence of strength. 1, 2 This term specifically refers to a static feeling of weakness that is not necessarily related to physical effort, distinguishing it from other related symptoms. 2

Important Clinical Distinctions

It is critical to differentiate asthenia from other symptoms that patients may confuse with general weakness:

  • Muscle weakness: Refers to objective loss of muscle strength or function, which can be measured through physical examination (e.g., reduced grip strength, inability to rise from a chair). 3
  • Dizziness: A sensation of lightheadedness or vertigo. 1
  • Dyspnea: Shortness of breath or difficulty breathing. 1
  • Fatigue: While often used interchangeably with asthenia, fatigue more specifically describes exhaustion that occurs with physical or intellectual effort and persists after rest. 4

Related Medical Terms

Several related terms describe specific manifestations or contexts of weakness:

  • Sarcopenia: Progressive loss of skeletal muscle mass, strength, and function, typically age-related but can be secondary to disease, inactivity, or nutritional deficiency. 3
  • Frailty: A state of vulnerability with reduced physiological reserve capacity, often including weakness as one of five diagnostic criteria. 3
  • Myasthenia: Specifically refers to fatigable or fluctuating muscle weakness, often with ocular or bulbar involvement. 3
  • Neurocirculatory asthenia: A historical term (also called Da Costa's syndrome) describing a chronic condition with fatigue, breathlessness, and other symptoms but normal physical examination. 5

Clinical Classification

Asthenia can be classified by duration:

  • Prolonged fatigue: Lasting more than one month. 1
  • Chronic fatigue: Duration greater than six months. 1
  • Chronic fatigue syndrome: A specific diagnosis of exclusion with defined international criteria, representing 0.2-0.7% of asthenia cases. 1
  • Senile asthenia syndrome: Used specifically for older adults, characterized by age-associated decrease in physiological reserve and function. 4

Clinical Significance

Asthenia is an extremely common presenting complaint, accounting for approximately 30% of ambulatory consultations. 1 Depression represents the most common underlying cause, accounting for approximately half of all cases. 1 Up to 20% of patients with asthenia remain without a definitive diagnosis despite thorough evaluation. 1

References

Research

Asthenia in primary care; The 3me mnemonic.

JPMA. The Journal of the Pakistan Medical Association, 2025

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

[Asthenic disorders correction with Recognan].

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2024

Research

Da Costa's syndrome or neurocirculatory asthenia.

British heart journal, 1987

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.