What is the cause of erythema (redness) of the toes?

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Last updated: April 11, 2025View editorial policy

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Differential Diagnosis for Toe Redness

  • Single most likely diagnosis
    • Cellulitis: This is a common and likely cause of toe redness, often resulting from a bacterial infection of the skin and soft tissues. It is characterized by redness, swelling, warmth, and pain.
  • Other Likely diagnoses
    • Fungal infection (e.g., athlete's foot): Fungal infections can cause redness, itching, and scaling of the skin on the toes.
    • Ingrown toenail: An ingrown toenail can cause redness, swelling, and pain around the nail.
    • Eczema (atopic dermatitis): Eczema can cause redness, itching, and dryness of the skin on the toes.
    • Psoriasis: Psoriasis can cause red, scaly patches on the toes.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
    • Gangrene: Gangrene is a serious condition that occurs when tissue dies due to a lack of blood supply. It can cause redness, swelling, and pain, and can lead to amputation if not treated promptly.
    • Deep vein thrombosis (DVT): DVT is a blood clot that forms in the deep veins of the leg. It can cause redness, swelling, and pain, and can lead to pulmonary embolism if not treated promptly.
    • Septic arthritis: Septic arthritis is a bacterial infection of the joint. It can cause redness, swelling, and pain, and can lead to joint destruction if not treated promptly.
  • Rare diagnoses
    • Erythromelalgia: Erythromelalgia is a rare condition that causes burning pain, redness, and heat in the hands and feet.
    • Complex regional pain syndrome (CRPS): CRPS is a rare condition that causes chronic pain, redness, and swelling in the affected limb.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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