Annual Screening Recommendations for a 47-Year-Old Male
A 47-year-old male should undergo annual blood pressure screening, colorectal cancer screening starting now (age 45-50), lipid profile assessment, diabetes screening with hemoglobin A1C, and should engage in shared decision-making about prostate cancer screening beginning at age 50 or now if at higher risk. 1, 2
Cardiovascular Screening
Blood Pressure
- Screen blood pressure at every clinical visit or at minimum annually. 3
- Blood pressure measurement should be performed using proper technique, and any elevated readings should be confirmed with measurements outside the clinical setting before initiating treatment. 3
- This represents the single most important screening test given hypertension affects 45% of adults and is a major risk factor for heart failure, myocardial infarction, stroke, and chronic kidney disease. 3
Lipid Profile
- Obtain a lipid profile (total cholesterol, LDL, HDL, triglycerides) now, as screening is recommended for men aged 40-75 years. 2, 4
- Non-fasting samples are acceptable for lipid screening. 2
- Repeat testing intervals should be every 6-12 months if risk factors are identified. 5
Metabolic Screening
Diabetes
- Screen with hemoglobin A1C, particularly if BMI ≥25 kg/m² with additional risk factors. 2
- Risk factors include first-degree relative with diabetes, high-risk race/ethnicity, history of cardiovascular disease, hypertension, HDL <35 mg/dL, or triglycerides >250 mg/dL. 2
- If results are normal, repeat testing every 3 years; if prediabetes is detected (A1C 5.7-6.4%), test yearly. 2
Comprehensive Metabolic Panel
- Obtain a comprehensive metabolic panel including electrolytes, creatinine with eGFR, and liver function tests to assess kidney and liver function. 2, 5
Cancer Screening
Colorectal Cancer
- Begin colorectal cancer screening now, as guidelines recommend starting at age 45. 1, 2
- Screening options include:
- All positive results on non-colonoscopy tests must be followed up with timely colonoscopy. 1, 2
- The choice between options should be based on personal preferences, risk factors, and test availability. 1
Prostate Cancer
- At age 47, initiate discussions about prostate cancer screening if the patient is African American or has a family history of prostate cancer; otherwise, defer formal screening discussions until age 50. 2
- For men at higher risk (African American or family history), screening discussions should begin at age 45. 2
- For average-risk men, PSA testing and digital rectal examination should be offered annually beginning at age 50. 2
- Use shared decision-making to weigh potential benefits (reduction in prostate cancer mortality) against harms (false positives, overdiagnosis, treatment complications). 1, 2
- If baseline PSA testing is performed and the value is ≤1.0 ng/mL, additional testing may be deferred until age 50; if >1.0 ng/mL, repeat at 1-2 year intervals. 6
Additional Laboratory Tests
Complete Blood Count
- Obtain CBC with differential to screen for anemia, infection, and blood disorders. 2
Urinalysis
Body Measurements
- Measure height and weight to calculate body mass index at each visit. 4
Critical Pitfalls to Avoid
- Do not delay colorectal cancer screening beyond age 45, as guidelines have recently lowered the recommended starting age from 50 to 45. 2
- Do not fail to confirm abnormal lipid or glucose results before making a diagnosis. 2
- Do not fail to assess family history, as this significantly impacts screening recommendations for diabetes, cardiovascular disease, and cancer. 5
- Provide counseling on diet, physical activity, tobacco cessation, and alcohol use at each visit. 2, 4