What is the approach to implementing Exposure and Response Prevention (ERP) therapy for a patient with Obsessive-Compulsive Disorder (OCD) as a Psychiatric Nurse Practitioner (Psych NP)?

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Last updated: January 11, 2026View editorial policy

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Implementing ERP for OCD as a Psychiatric Nurse Practitioner

As a Psych NP, you should refer patients with OCD to a therapist specifically trained in ERP while managing pharmacotherapy, as ERP is a specialized psychotherapy technique that requires dedicated training in exposure-based interventions and is outside the typical scope of NP practice. 1, 2

Understanding Your Role vs. Therapist Role

What ERP Actually Entails

  • ERP involves gradual exposure to fear-provoking stimuli combined with instructions to abstain from compulsive behaviors, requiring specialized training in exposure hierarchy development and response prevention techniques 2
  • The therapy demands intensive between-session homework assignments, which are the strongest predictor of good outcomes and require therapist expertise to design and monitor 1, 2
  • ERP typically requires 10-20 hours of direct therapist contact over 9-12 weeks, with twice-weekly sessions initially being most effective 3, 4

Your Primary Responsibilities as a Psych NP

Provide comprehensive psychoeducation at the initial visit:

  • Explain that OCD is a common, well-understood disorder with effective treatments that can achieve at least partial symptom reduction and improved quality of life 1
  • Address stigma and shame that often delays treatment seeking 1, 5
  • Educate about the biological and psychological underpinnings of OCD 1

Initiate or optimize pharmacotherapy:

  • Start an SSRI as first-line medication, using higher doses than typically used for depression (e.g., fluoxetine 60-80mg, sertraline 200mg, escitalopram 20-30mg) 1, 2
  • Allow 8-12 weeks at adequate doses before determining treatment response 2
  • For severe OCD or comorbid major depression, combine SSRI with referral for CBT/ERP rather than using either alone 1, 2

Coordinate care with the ERP therapist:

  • Refer to therapists specifically trained in ERP (not just general CBT practitioners) 1, 2
  • Monitor medication adherence and side effects while the therapist conducts ERP 1
  • Address family accommodation behaviors that may undermine ERP effectiveness 1

When You Might Provide Limited ERP-Adjacent Support

Psychoeducation About ERP Principles

  • Explain that ERP works by helping patients face feared situations without performing compulsions, allowing anxiety to naturally decrease 2
  • Normalize that anxiety will initially increase during exposures before improving 6
  • Emphasize the critical importance of homework adherence between therapy sessions 1, 7

Supporting Ongoing ERP Treatment

  • Encourage patients to complete between-session exposures prescribed by their therapist 7
  • Reinforce progress and identify "innovative moments" where patients successfully resisted compulsions 6
  • Avoid providing reassurance about obsessional content, as this functions as a compulsion 5

Treatment Algorithm for Your Practice

Step 1: Initial Assessment and Treatment Planning

  • Assess OCD severity using Y-BOCS (Yale-Brown Obsessive-Compulsive Scale) 1
  • Evaluate for comorbid depression, which affects treatment sequencing 2
  • Determine if symptoms are mild-moderate (ERP referral alone) or severe (combined SSRI + ERP) 1, 2

Step 2: First-Line Interventions

  • Mild-moderate OCD: Refer for ERP therapy as monotherapy 2
  • Severe OCD or comorbid depression: Start SSRI AND refer for ERP simultaneously 1, 2
  • Provide psychoeducation and address family accommodation at this visit 1

Step 3: Monitoring and Optimization (8-12 weeks)

  • If inadequate response to SSRI monotherapy, add ERP referral if not already done 2
  • If inadequate response to ERP alone, add SSRI 2
  • Optimize SSRI dose to higher end of range before switching agents 2

Step 4: Treatment-Resistant OCD

  • Switch to different SSRI or clomipramine 2
  • Consider augmentation with aripiprazole 5-15mg, brexpiprazole, or memantine 2
  • Refer for intensive ERP (multiple sessions per week or day-treatment programs) 1, 4
  • Consider glutamatergic agents like N-acetylcysteine as augmentation 2

Alternative Delivery Methods You Can Recommend

When in-person ERP is inaccessible:

  • Video teletherapy ERP achieves similar outcomes to in-person treatment with large effect sizes (g=1.0) and 62.9% response rates 3
  • Computer-assisted self-help programs with ERP components lasting more than 4 weeks show efficacy, though with higher dropout rates 8, 1
  • These digital interventions work best when they include psychoeducation, cognitive elements, and structured ERP exercises 8

Critical Pitfalls to Avoid

Do not attempt to conduct formal ERP yourself without specialized training in exposure therapy techniques, as improper implementation can worsen symptoms or cause treatment dropout 4

Avoid providing reassurance about obsessional content during medication management visits, as this reinforces the OCD cycle and undermines concurrent ERP 5

Do not use standard depression/anxiety doses of SSRIs for OCD—higher doses are required and underdosing is a common cause of treatment failure 1, 2

Do not discontinue treatment prematurely—OCD is typically chronic and requires long-term management with booster sessions every 3-6 months after initial improvement 1

Address family accommodation explicitly, as family members often unknowingly maintain OCD symptoms by participating in rituals or providing excessive reassurance 1, 5

References

Guideline

Management of Obsessive-Compulsive Disorder (OCD)

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Treatment of Obsessive-Compulsive Disorder (OCD)

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2026

Guideline

Treatment for Relationship Obsessive-Compulsive Disorder (ROCD)

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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