What is a proposed prevention strategy for maternal sepsis in pregnant women?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: January 11, 2026View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Prevention Strategy for Maternal Sepsis

Screening for asymptomatic bacteriuria for prevention of pyelonephritis (option c) is the correct prevention strategy for maternal sepsis.

Why This is the Correct Answer

While the provided evidence focuses primarily on recognition, diagnosis, and management of established maternal sepsis rather than primary prevention strategies, screening for asymptomatic bacteriuria represents a well-established preventive measure in obstetric care. Untreated asymptomatic bacteriuria in pregnancy can progress to pyelonephritis, which is a known source of maternal sepsis 1, 2.

Why the Other Options Are Incorrect

Option A: Prophylactic Antibiotics 120 Minutes Prior to Cesarean

  • The timing is wrong - standard practice calls for prophylactic antibiotics within 60 minutes (not 120 minutes) before skin incision for cesarean delivery 2
  • While antibiotic prophylaxis for cesarean delivery does prevent surgical site infections, the 120-minute timeframe makes this option incorrect

Option B: Vaginal Prep Prior to Vaginal Delivery

  • Vaginal preparation before vaginal delivery is not a standard prevention strategy for maternal sepsis 2
  • The evidence does not support routine vaginal antiseptic preparation for preventing sepsis in vaginal deliveries

Option D: Handwashing by Patients During Second Stage of Labor

  • While hand hygiene is important for healthcare providers, patient handwashing during active labor (second stage) is not a recognized sepsis prevention strategy 2
  • This would be impractical during active pushing and is not evidence-based for sepsis prevention

Key Prevention Principles

Early recognition and screening are critical because approximately half of maternal sepsis cases occur in the postdischarge postpartum period, making outpatient recognition crucial 3. Maternal sepsis is the second leading cause of preventable maternal mortality 3.

Prevention focuses on:

  • Identifying and treating infections before they progress to sepsis 1, 2
  • Screening for asymptomatic bacteriuria to prevent progression to pyelonephritis 1
  • Appropriate antibiotic prophylaxis for surgical procedures at correct timing 2
  • Early recognition of infection through screening protocols 4, 2

References

Research

Maternal sepsis.

American journal of obstetrics & gynecology MFM, 2020

Research

Society for Maternal-Fetal Medicine Consult Series #67: Maternal sepsis.

American journal of obstetrics and gynecology, 2023

Guideline

Postpartum Sepsis Diagnosis and Management

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Management of Suspected Sepsis in Pregnancy

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.