Is Hepatitis B (HBV) considered a sexually transmitted disease (STD)?

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Is Hepatitis B Considered a Sexually Transmitted Disease?

Yes, Hepatitis B is definitively considered a sexually transmitted disease—sexual contact is one of the two primary modes of HBV transmission among adults in the United States, accounting for approximately 63% of new infections (39% heterosexual transmission and 24% among men who have sex with men). 1

Primary Transmission Routes in Adults

The CDC explicitly identifies sexual transmission as a major route of HBV spread: 1

  • Sexual contact accounts for the majority of adult HBV infections in developed countries 1, 2
  • Percutaneous exposure to blood (injection drug use, occupational exposure) is the other primary route 1
  • HBV is transmitted efficiently through both heterosexual and homosexual contact 1

Why HBV Qualifies as an STD

Infectious body fluids: Semen and vaginal secretions contain infectious HBV and are concentrated enough to transmit disease through sexual contact 1

Epidemiologic evidence: 1, 3

  • Prospective studies show 20-27% secondary attack rates among serosusceptible spouses of HBV-infected persons 3
  • The highest incidence of acute hepatitis B occurs in adults aged 25-45 years, the sexually active population 1
  • Serologic evidence of HBV infection ranges from 10-40% among adults in STD clinics 1

Risk factors mirror other STDs: 1

  • Having unprotected sex with an infected partner
  • Having multiple sex partners
  • History of other sexually transmitted infections
  • Among MSM: multiple partners, anal intercourse, and history of other STDs

Clinical Management as an STD

The CDC's STD Treatment Guidelines explicitly include HBV management: 1, 4

  • Screen with HBsAg in patients presenting with STI concerns 4
  • Partner notification and postexposure prophylaxis (HBIG plus vaccine) must be provided to sexual contacts within 14 days 1, 4
  • Condom counseling is recommended for sex partners of HBsAg-positive persons until immunity is documented 1
  • Co-testing for HIV, syphilis, gonorrhea, and chlamydia is recommended given overlapping transmission routes 4

Important Caveats

HBV has multiple transmission routes beyond sexual contact: 1

  • Perinatal transmission (mother to infant)
  • Household contact through sharing razors/toothbrushes
  • Healthcare-associated exposures
  • Contaminated surfaces (virus remains viable for >7 days) 1

Not all HBV is sexually acquired: The classification as an STD applies primarily to adult-acquired infections in developed countries, whereas perinatal and early childhood transmission predominate in endemic regions 1

Prevention strategy: Vaccination is recommended for all adults at risk for sexual transmission, including those seeking STD evaluation, MSM, and persons with multiple sex partners 1, 5

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Sexual transmission of hepatitis B.

Current opinion in infectious diseases, 2005

Guideline

Hepatitis B Screening for Patients with Sexually Transmitted Infection Concerns

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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