Duration of Zerodol SP (Diclofenac) Treatment
For acute pain conditions, Zerodol SP (diclofenac) should be used for the shortest duration possible, typically 3-5 days maximum, and should not exceed 7 days without medical reassessment. 1, 2, 3
Recommended Treatment Duration by Pain Type
Acute Pain (Most Common Use)
- Initial treatment: 3-5 days maximum for most acute painful conditions including musculoskeletal injuries, dental pain, headache, and minor trauma 1, 3
- Single dose or short-term use (1-2 days) is often sufficient for mild acute pain episodes 3
- Maximum OTC duration: 5 days for pain without medical supervision 3
Specific Acute Conditions
- Dental extraction pain: 1-7 days, with most patients requiring only 3-5 days 1, 3
- Acute lower back pain: Typically 3-7 days, as pain substantially decreases by day 4 1, 3
- Dysmenorrhea (menstrual pain): Use only during symptomatic days, typically 2-3 days per cycle 3
- Cold/flu symptoms with fever: Maximum 3 days for fever 3
Chronic Pain Conditions
- Osteoarthritis or rheumatoid arthritis: While diclofenac can be used longer-term under medical supervision, reassessment is required every 1-4 weeks initially, then every 3 months 4, 5, 6
- Continuous use beyond 3 months requires gastric protection (proton pump inhibitor or H2 blocker) due to increased gastrointestinal bleeding risk 2
Critical Safety Considerations
Why Short Duration Matters
- Gastrointestinal toxicity increases significantly with duration of use, including risk of ulceration and bleeding 2, 5
- Cardiovascular and renal risks accumulate with prolonged NSAID exposure 2
- Most acute pain conditions resolve within 3-7 days, making longer treatment unnecessary 1, 3
When to Stop Immediately
- If pain persists beyond 5-7 days, stop diclofenac and seek medical evaluation to reassess the underlying cause 3
- Development of gastrointestinal symptoms (abdominal pain, black stools, heartburn) 2, 5
- Signs of allergic reaction or skin rash 5, 3
Dosing Strategy for Short-Term Use
Flexible Dosing Approach
- Initial dose: 25mg (two 12.5mg tablets) for acute pain 3
- Maintenance: 12.5-25mg every 4-6 hours as needed 3
- Maximum daily dose: 75mg (six 12.5mg tablets) for OTC use 3
- Always take with food to minimize gastrointestinal side effects 2
Common Pitfall to Avoid
Do not continue taking diclofenac "just in case" pain returns after the acute episode resolves—this unnecessarily increases risk without benefit 1. Many patients mistakenly continue NSAIDs beyond the acute pain phase, exposing themselves to cumulative toxicity.
Alternative Approach for Inadequate Pain Control
If pain is not adequately controlled after 3 days of diclofenac: