Laparoscopic Appendectomy: The Preferred Approach
Laparoscopic appendectomy is the recommended first-line surgical treatment for acute appendicitis and should be performed over open appendectomy whenever laparoscopic equipment and expertise are available. 1, 2, 3
Surgical Approach Selection
Primary Recommendation: Laparoscopic Technique
The conventional three-port laparoscopic appendectomy is the gold standard approach, offering multiple advantages over open surgery: 1, 2, 3
- Less postoperative pain with reduced analgesic requirements 4, 5, 6
- Lower surgical site infection rates (3.8% vs 14% in comparative studies) 5, 6
- Shorter hospital stays (mean 2.6 days vs 3.3 days for open) 4, 5, 6
- Earlier return to work and normal activities 2, 7
- Better quality of life scores 1, 2
The laparoscopic approach is particularly advantageous for obese patients, older patients, those with comorbidities, and pregnant patients. 3
When Open Appendectomy May Be Necessary
Open appendectomy remains appropriate when: 1, 2
- Laparoscopic expertise is unavailable 2
- Equipment is not accessible 1
- Conversion is required intraoperatively (occurs in <1% of cases) 4
Maintain a low threshold for conversion to open procedure if technical difficulties arise during laparoscopy. 2
Timing of Surgery
Appendectomy should be performed within 24 hours of admission to minimize complications. 1, 2, 3, 8
- Delays beyond 24 hours increase adverse outcomes including perforation risk 1, 3, 8
- For complicated appendicitis with perforation, early appendectomy within 8 hours is recommended 1, 3
- Short in-hospital delays up to 24 hours are safe for uncomplicated cases 1
Technical Considerations
Operative Technique Specifics
Use conventional three-port laparoscopic technique rather than single-incision approaches: 1, 2, 3
- Shorter operative times (mean 44-55 minutes) 4, 5
- Less postoperative pain 1, 3
- Lower wound infection rates 1, 3
For mesoappendix dissection: Use monopolar or bipolar electrocoagulation as cost-effective techniques 2, 3
For stump closure: Use endoloops/suture ligation or polymeric clips 2, 3
Simple ligation is preferred over stump inversion in both laparoscopic and open approaches 3
Intraoperative Management
- Administer single preoperative dose of broad-spectrum antibiotics 0-60 minutes before incision 2, 8
- In complicated appendicitis with collections, use suction alone rather than irrigation 3
- Routine intraoperative irrigation does not prevent abscess formation and may be avoided 1
Management of Complicated Appendicitis
Appendiceal Abscess or Phlegmon
When laparoscopic expertise is available, early laparoscopic appendectomy is preferable to non-operative management for patients with appendiceal phlegmon or abscess: 1, 2
- Reduces length of hospital stay 1
- Decreases need for readmissions 1
- Lower incidence of bowel resection (3.3% vs 17.1%) compared to initial conservative management 1, 2
If laparoscopic expertise is unavailable: 2
- Percutaneous image-guided drainage plus antibiotics when interventional radiology is accessible 1, 3
- Surgery if drainage is not available 1
Postoperative Care
Do not place abdominal drains following appendectomy for complicated appendicitis in adults or children 2, 3
For uncomplicated appendicitis: No postoperative antibiotics are needed 2
For complicated appendicitis with adequate source control: Limit antibiotics to 3-5 days maximum 2
Special Populations and Situations
Outpatient Laparoscopic Appendectomy
Outpatient laparoscopic appendectomy is safe and feasible for uncomplicated appendicitis when an ambulatory setting with well-defined protocols is available: 1, 2, 3
- Complication rates comparable to inpatient procedures (2.4% vs 11.7%) 9
- Earlier recovery and cost savings 1, 3
The Normal-Appearing Appendix
Always remove the appendix during surgery even if it appears macroscopically normal when the patient is symptomatic and no other pathology is found: 2, 3, 8
- Surgeon's visual judgment of early appendicitis is highly inaccurate 2, 8
- Routine histopathological examination identifies unexpected findings including malignancy 2, 3, 8
Follow-Up Considerations
For patients ≥40 years old with complicated appendicitis: 2
- Perform both colonoscopy and interval full-dose contrast-enhanced CT scan
- Higher incidence of appendicular neoplasms (3-17%) in this age group 2
Interval appendectomy is not routinely recommended after non-operative management in young adults (<40 years) and children, but should be performed for recurrent symptoms 1, 2
Critical Pitfalls to Avoid
- Never delay surgery beyond 24 hours from admission without compelling reason 1, 3, 8
- Do not leave the appendix in place if it appears normal during surgery in symptomatic patients 2, 3, 8
- Always send specimens for histopathology to avoid missing unexpected findings 2, 3, 8
- Do not use single-incision technique as routine approach given inferior outcomes 1, 2, 3
- Avoid routine irrigation in complicated cases as it does not prevent abscess formation 1, 3
Alternative: Antibiotic-First Approach
While laparoscopic appendectomy remains the gold standard, antibiotic therapy alone may be considered in highly selected cases of uncomplicated appendicitis: 2, 7
- Approximately 30% require subsequent appendectomy within one year 2, 3
- CT findings that predict antibiotic failure include: appendicolith, mass effect, or appendiceal diameter >13 mm 7
- Recommend surgery rather than antibiotics-first in patients with these high-risk CT findings who are fit for surgery 7