What is the typical age range for molluscum contagiosum (a viral skin infection) to occur?

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Typical Age Range for Molluscum Contagiosum

Molluscum contagiosum most commonly affects children aged 1-10 years, with peak incidence in the 5-10 year age group, though it can occur in sexually active adults and immunocompromised individuals at any age. 1, 2

Age Distribution in Children

  • The highest incidence occurs in children aged 5-10 years, followed by the 1-5 year age group, with less frequent occurrence in children aged 10-14 years and rare cases in infants under 1 year. 3

  • Children represent approximately 85% of all molluscum contagiosum cases, with the condition typically affecting the trunk, face, and extremities in this population. 3

  • The male-to-female ratio in children is approximately 1.6:1, suggesting relatively equal distribution between sexes in the pediatric population. 3

Age Distribution in Adults

  • In adults, molluscum contagiosum is most commonly seen in the 14-20 year age group, with decreasing frequency in older age groups (20-26 years, 26-34 years, and 34-40 years). 3

  • Adult cases show a higher male predominance with a male-to-female ratio of 3.3:1, likely reflecting sexual transmission patterns. 3

  • In sexually active adults, lesions characteristically involve the genital area and the condition is regarded as a sexually transmitted infection. 4

Special Populations

  • Immunocompromised individuals, particularly those with HIV/AIDS, can develop molluscum contagiosum at any age with more extensive, atypical presentations including giant molluscum and disseminated lesions. 4, 3

  • HIV-positive patients may present with multiple large lesions with minimal inflammation, and the onset can be part of immune reconstitution inflammatory syndrome (IRIS). 4

Clinical Course Considerations

  • Lesions typically persist for 6-12 months but can last up to 4-5 years without treatment, regardless of age group. 1, 2

  • The condition is self-limited in immunocompetent individuals, though treatment may be indicated to prevent autoinoculation, transmission, and associated complications. 5

References

Guideline

Molluscum Contagiosum Treatment and Management

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Physical Examination Findings of Molluscum Contagiosum

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

[Mollusca contagiosa. From paediatric dermatology to sexually transmitted infection].

Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 2009

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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