Management of Stye (Hordeolum) in Children
Begin with warm compresses applied to the affected eyelid for 10-15 minutes, 3-4 times daily, combined with gentle eyelid hygiene using diluted baby shampoo, and add topical antibiotic ointment (erythromycin 0.5%) if no improvement occurs after 48-72 hours or if signs of spreading infection develop. 1
Initial Conservative Treatment (First-Line)
- Apply warm compresses to the affected eyelid for 10-15 minutes, 3-4 times daily to promote spontaneous drainage 1
- Clean the eyelid margin gently with diluted baby shampoo or commercially available eyelid scrubs to maintain good eyelid hygiene 1
- Instruct the child to avoid squeezing or manipulating the lesion, as this spreads infection to surrounding tissues 1
- Continue this conservative approach for 48-72 hours before escalating therapy 1
When to Add Topical Antibiotics
Add topical antibiotics if the stye has not improved after 48-72 hours of warm compresses OR if signs of spreading cellulitis appear. 1
- Apply erythromycin 0.5% ophthalmic ointment to the eyelid margin 2-3 times daily for 5-7 days 1
- Bacitracin ointment is an alternative option for children 2 years and older, applied 1-3 times daily to the affected area 2
- Recent evidence supports shorter antibiotic courses (5 days) as equally effective as longer courses (7-10 days) for uncomplicated cases 1
When to Prescribe Oral Antibiotics
Oral antibiotics are indicated when preseptal cellulitis develops, multiple hordeola are present with systemic infection signs, or the child has fever or appears systemically ill. 1
- First-line oral agent: Cephalexin 25-50 mg/kg/day divided into 3-4 doses for 5-7 days, providing coverage for methicillin-sensitive Staphylococcus aureus 1
- If MRSA is suspected: Clindamycin 10-13 mg/kg/dose three times daily (maximum 40 mg/kg/day) for 5-7 days, but only if local clindamycin resistance rates are <10% 1
Red Flags Requiring Urgent Ophthalmology Referral
- Recurrent hordeola occurring in the same location 1
- Vision changes or eye pain 1
- Proptosis or restricted eye movements 1
- Underlying chronic blepharokeratoconjunctivitis 1
Critical Pitfall: Don't Dismiss Recurrent Styes as Benign
Children with recurrent styes have an increased risk of developing adult rosacea and may represent early ocular rosacea before facial manifestations appear. 3
- Recurrent styes warrant evaluation for underlying blepharitis, meibomian gland dysfunction, or ocular rosacea 3, 1
- Without treatment, severe staphylococcal blepharitis may lead to eyelash loss, eyelid scarring with trichiasis, and corneal scarring 3
- The incidence of ulceration and perforation complications is greater in children compared to adults with blepharitis 3
- Examine for eyelid margin findings: telangiectasia, meibomian gland orifice narrowing/pouting, cylindrical dandruff at eyelash base, and blood-tinged debris 3
- Asymmetry of ocular involvement suggests ocular rosacea in children 3
Prevention Strategies for Recurrent Cases
- Implement daily eyelid hygiene with warm compresses and gentle lid scrubs 1
- Treat underlying blepharitis or seborrheic dermatitis 1
- Ensure the child avoids touching or rubbing the eyes and maintains good hand hygiene 1
Special Considerations
- In children with pediculosis palpebrarum (pubic lice) causing blepharitis, consider sexual abuse and perform appropriate evaluation 3
- Children on isotretinoin for severe acne have increased S. aureus colonization and blepharitis risk 3
- Children on dupilumab for atopic dermatitis experience conjunctivitis, keratitis, and blepharitis in 32-55% of cases 3