What are the signs and symptoms of costochondritis in an adult with sudden sharp stabbing one-sided chest pain at the apex area when coughing or breathing deeply?

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Signs and Symptoms of Costochondritis

Costochondritis presents with reproducible chest wall tenderness on palpation over the costochondral junctions, typically accompanied by sharp, localized pain that worsens with movement, deep breathing, or coughing.

Cardinal Clinical Features

Tenderness on palpation is the hallmark finding that distinguishes costochondritis from other causes of chest pain:

  • Systematic palpation of the costochondral joints elicits reproducible tenderness at the affected sites 1
  • Pain can be localized with one fingertip, particularly over costochondral junctions 2
  • The tenderness directly reproduces the patient's presenting chest pain 3, 4

Pain characteristics that are typical of costochondritis include:

  • Sharp, stabbing, or "knifelike" quality rather than pressure or heaviness 2
  • Pleuritic nature—pain worsens with deep breathing, coughing, or respiratory movements 2, 1
  • Exacerbation with chest wall movement or arm motion 2
  • Localized to the anterior chest wall, most commonly affecting the second through fifth costochondral junctions 3

Important Distinguishing Features

The pain pattern helps differentiate costochondritis from cardiac causes:

  • Pain reproduced by palpation or movement strongly suggests musculoskeletal origin 2
  • Sharp, stabbing pain brought on by respiratory movements is not characteristic of myocardial ischemia 2
  • However, 7% of patients with pain reproducible on palpation may still have acute coronary syndrome, so reproduction of pain does not completely exclude cardiac disease 2

Clinical Context and Demographics

Costochondritis occurs more frequently in certain populations:

  • Women comprise approximately 69% of emergency department cases with costochondritis 4
  • The condition is common, affecting 30% of patients presenting with chest pain in emergency settings 4
  • Most cases are self-limited and resolve within weeks, though 55% may have persistent symptoms at one year 4

Critical Caveat for Your Clinical Scenario

In a patient with sudden sharp stabbing one-sided chest pain at the apex area worsening with coughing or deep breathing, you must first rule out life-threatening causes before diagnosing costochondritis:

  • Sharp or stabbing pain was present in 22% of patients ultimately diagnosed with acute myocardial ischemia 2
  • Pleuritic features were present in 13% of patients with acute ischemia 2
  • Patients older than 35 years or those with cardiac risk factors require electrocardiogram to exclude cardiac causes 3
  • Chest radiography is useful as initial imaging to evaluate for pneumothorax, pneumonia, or other conditions that may simulate chest wall pain 2, 1

Physical Examination Approach

To establish the diagnosis of costochondritis:

  • Perform focused cardiovascular examination initially to rule out acute coronary syndrome, aortic dissection, or pulmonary embolism 1
  • Palpate costochondral joints systematically to identify tender areas 1
  • Assess whether pain increases with deep breathing, coughing, or movement 1
  • Check for absence of friction rub, which would indicate pleural or pericardial involvement rather than costochondral pain 1

References

Guideline

Examination of Costochondral Pain

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Costochondritis: diagnosis and treatment.

American family physician, 2009

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Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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