What is the recommended patient position for a prostate biopsy, specifically for a transrectal ultrasound (TRUS)-guided procedure?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: January 20, 2026View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Patient Position for TRUS-Guided Prostate Biopsy

The left lateral decubitus position is the standard recommended position for transrectal ultrasound (TRUS)-guided prostate biopsy. 1

Standard Positioning Protocol

The left lateral decubitus position is explicitly recommended in clinical guidelines for TRUS-guided prostate biopsy procedures. 1 This positioning allows optimal access for the transrectal ultrasound probe and biopsy needle while maintaining patient comfort during the procedure. 1

Evidence Supporting Left Lateral Decubitus Position

Pain and tolerability data favor the lithotomy position over lateral decubitus, though guidelines still recommend lateral positioning. 2, 3 Two comparative studies found:

  • Lithotomy position resulted in lower pain scores (median VAS 30 vs 45) and better patient willingness to undergo repeat procedures (96.6% vs 86.7%) compared to left lateral decubitus. 2, 3
  • Patients in lithotomy position required less additional analgesia (14.3% vs 37.1%) and experienced less post-biopsy hematuria. 3
  • However, despite these findings, the established guideline recommendation remains left lateral decubitus position for standard TRUS-guided biopsy. 1

Alternative Positioning for MRI-Guided Biopsies

For MRI-guided prostate biopsies, the supine position is preferred and technically feasible. 4, 5 This differs from standard TRUS-guided procedures because:

  • Supine positioning is more patient-friendly and comfortable during prolonged MRI procedures. 4
  • Dedicated MR-compatible biopsy devices allow successful supine positioning without modifying the MRI table. 4
  • Positional changes between supine diagnostic MRI and lateral decubitus biopsy can cause prostate translocation ≥5 mm in 20% of patients, potentially affecting targeting accuracy. 6

Clinical Pitfalls to Avoid

Do not assume patient position is irrelevant to procedural outcomes. Position affects both patient comfort and technical accuracy:

  • The prostatic base demonstrates the largest positional differences between supine and lateral positions. 6
  • Larger bladder volumes can minimize prostate translocation in the latero-lateral direction. 6
  • When using MRI/US fusion guidance, be aware that position-related prostate translocation compounds software misregistration errors. 6

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.