What are the risks and benefits of taking Snap Supplements Nitric Oxide Booster Supplement with L-Arginine and L-Citrulline essential amino acids and Ginseng Root, and is it safe to take with Adderall (amphetamine and dextroamphetamine), Lexapro (escitalopram), and Ozempic (semaglutide)?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: April 15, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

From the Research

I strongly advise against taking Snap Supplements Nitric Oxide Booster with Adderall, Lexapro, and Ozempic without medical supervision due to potential interactions and risks to your health. This supplement contains L-arginine, L-citrulline, and ginseng root, which may offer benefits like improved blood flow, enhanced exercise performance, and potential cardiovascular support by increasing nitric oxide production in the body, as supported by studies such as 1 and 2. However, it carries risks including digestive issues, blood pressure changes, and possible allergic reactions.

More concerning are the potential interactions with your medications:

  • Ginseng may interact with Adderall, potentially increasing stimulant effects
  • It might also interact with Lexapro, affecting serotonin levels, as suggested by research on the involvement of NMDA receptors and L-arginine-nitric oxide-cyclic guanosine monophosphate pathway in the antidepressant-like effects of escitalopram 3
  • The supplement could theoretically affect blood sugar levels, which is relevant when taking Ozempic
  • Additionally, L-arginine might enhance the blood pressure-lowering effects of medications, as noted in studies on the role of L-arginine in nitric oxide synthesis and health in humans 2

The benefits of L-citrulline supplementation on cardiometabolic health, including its potential to improve blood pressure and exercise performance, are also important to consider, as discussed in 4. Furthermore, the impact of nitric oxide enhancing supplements on resistance exercise performance has been demonstrated in studies such as 5.

Before taking this supplement, consult your healthcare provider who knows your complete medical history and can evaluate these specific risks for your situation. The combination of prescription medications with supplements always warrants professional guidance to ensure safety.

References

Research

Dietary supplements for improving nitric-oxide synthesis.

Journal of preventive medicine and hygiene, 2022

Research

Role of L-Arginine in Nitric Oxide Synthesis and Health in Humans.

Advances in experimental medicine and biology, 2021

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.