How do you perform and interpret an ECG in a patient?

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How to Perform and Interpret an ECG

Proper ECG Acquisition Technique

Accurate electrode placement is the single most critical technical factor—precordial lead misplacement of as little as 2 cm can result in diagnostic errors, particularly for anteroseptal infarction and ventricular hypertrophy. 1

Electrode Placement Standards

  • Place V1 at the 4th intercostal space, right sternal border 1
  • Place V2 at the 4th intercostal space, left sternal border 1
  • Position V3 midway between V2 and V4 1
  • Place V4 at the 5th intercostal space, midclavicular line 1
  • Position V5 at the anterior axillary line, same horizontal level as V4 1
  • Place V6 at the midaxillary line, same horizontal level as V4 and V5 1
  • Common pitfall: V1 and V2 are frequently placed too high (superior misplacement in >50% of cases), and left precordial leads are often placed too low and leftward (>33% of cases) 1

Technical Recording Standards

  • Use a minimum high-frequency response of 150 Hz for adults and adolescents, 250 Hz for children 2
  • Set sampling rate to at least 500 Hz, preferably 1200 Hz for digital systems 2
  • Apply appropriate low-frequency filters to reduce baseline drift while preserving ST-segment morphology 2
  • Verify electrode contact quality before recording to minimize baseline wander and electrical interference 2
  • For serial tracings in acute settings, use skin marking to ensure reproducible lead placement 1

Systematic ECG Interpretation Approach

Always interpret the ECG in the context of the patient's clinical presentation—the same ECG pattern may have different implications depending on symptoms. 1, 2

Step 1: Rate and Rhythm Analysis

  • Calculate heart rate by counting QRS complexes in a 6-second strip and multiplying by 10, or use 300 divided by the number of large boxes between consecutive R waves 2
  • Normal sinus rhythm: rate 60-100 bpm in adults, P wave before each QRS with consistent PR interval 2
  • Identify any irregularities suggesting premature beats, pauses, or atrial fibrillation 2

Step 2: Interval Measurements

  • Measure PR interval (normal: 120-200 ms) to assess AV conduction 2
  • Evaluate QRS duration (normal: <120 ms) to identify ventricular conduction delays 2
  • Calculate QTc using Bazett's formula (normal: <450 ms for men, <460 ms for women) 2
  • Measure QRS duration in a lead with an initial Q wave for accuracy 2

Step 3: Axis Determination

  • Examine leads I and aVF to determine electrical axis 2
  • Normal axis: +90° to -30° (positive in both leads I and aVF) 2
  • Left axis deviation: -30° to -90° (positive in lead I, negative in aVF) 2
  • Right axis deviation: +90° to +180° (negative in lead I, positive in aVF) 2

Step 4: Chamber Enlargement Assessment

  • Apply Sokolow-Lyon criterion for left ventricular hypertrophy: S in V1 + R in V5 or V6 >3.5 mV 2
  • Note that QRS voltage criteria decline with age and vary by population 2
  • Assess for atrial enlargement patterns 2

Step 5: Ischemia and Infarction Evaluation

  • Examine for ST-segment elevation (>0.1 mV in limb leads or >0.15-0.2 mV in precordial leads) indicating acute injury 2
  • Look for T-wave abnormalities (inversion, hyperacute, flattening) 2
  • Identify pathological Q waves (>0.04 seconds or >25% of R wave amplitude) suggesting myocardial infarction 2
  • Note the location of abnormalities to determine affected coronary territory 2

Critical Interpretation Pitfalls to Avoid

Computer-generated ECG interpretations are not recognized as properly interpreted without qualified physician review—automated systems still produce frequent errors. 1, 2

Common Technical Errors

  • Avoid misplacement of precordial electrodes, which can alter computer-based diagnostic statements in up to 6% of recordings 1
  • Recognize that inadequate high-frequency response causes systematic underestimation of signal amplitude and smoothing of Q waves 2
  • Do not accept computer interpretation without physician verification 2
  • Always compare with previous ECGs when available to identify important changes 2

Interpretation Considerations

  • Noncardiologists are more influenced by patient history when interpreting ECGs than cardiologists 1, 2
  • ECG interpretation varies greatly even among expert electrocardiographers 1
  • The same ECG finding may have different implications depending on clinical symptoms 1, 2
  • Consider normal variants in athletes, such as sinus bradycardia ≥30 bpm 2
  • In children >1 month, T waves are often inverted in leads V1, V2, and V3 2

Competency Requirements

Residency training in internal medicine with Advanced Cardiac Life Support instruction is sufficient for bedside interpretation of resting 12-lead ECGs in routine and emergency situations. 1

  • Successful completion of residency, board certification, and ACLS training provides reasonable documentation of competency 1
  • For interpreting ECGs when unfamiliar with the patient's clinical status, additional experience or standardized testing may be needed 1
  • Continuing medical education through seminars or self-assessment programs is encouraged for physicians who read ECGs infrequently 1, 2
  • Periodic retraining in proper lead positioning should be routine for all personnel recording ECGs 1

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

EKG Interpretation Guidelines

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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