What is the list of antipsychotic medications?

From the Guidelines

Antipsychotics that should be considered for use include risperidone, olanzapine, quetiapine, aripiprazole, ziprasidone, paliperidone, lurasidone, asenapine, brexpiprazole, cariprazine, and clozapine, as they are associated with fewer extrapyramidal side effects compared to typical antipsychotics like haloperidol, chlorpromazine, fluphenazine, perphenazine, thioridazine, and trifluoperazine 1. When selecting an antipsychotic, it is essential to consider the potential side effects and the individual patient's needs.

• Atypical antipsychotics, such as risperidone and olanzapine, are generally preferred due to their lower risk of extrapyramidal side effects, as noted in the study published in the British Journal of Psychiatry 1.
• The study also suggests that initial target doses for most patients are risperidone 2 mg/day or olanzapine 7.5–10.0 mg/day, highlighting the importance of careful dosing to minimize side effects 1.
• In contrast, typical antipsychotics like haloperidol are associated with a higher risk of extrapyramidal side effects, as discussed in the guidelines for managing Alzheimer's disease 1. Some antipsychotics are available in long-acting injectable forms, which can improve medication adherence for patients who struggle with daily oral medications.
• Examples of long-acting injectable antipsychotics include risperidone Consta, paliperidone palmitate, aripiprazole Maintena, and olanzapine pamoate, as mentioned in the context of managing psychotic disorders 1. It is crucial to weigh the benefits and risks of each antipsychotic and consider individual patient factors, such as medical history and potential interactions with other medications, to ensure the best possible outcome.
• The guidelines emphasize the importance of careful assessment and monitoring to minimize the risk of side effects and optimize treatment outcomes 1.

From the FDA Drug Label

In clinical trial and postmarketing experience, events of leukopenia/neutropenia have been reported temporally related to atypical antipsychotic agents, including quetiapine. Agranulocytosis has also been reported In clinical trial and postmarketing experience, events of leukopenia/neutropenia have been reported temporally related to atypical antipsychotic agents, including quetiapine. Quetiapine and olanzapine are both atypical antipsychotic agents.

The list of antipsychotics mentioned includes:

• Quetiapine
• Olanzapine 2 3

From the Research

List of Antipsychotics

• Haloperidol 4, 5, 6
• Olanzapine 4, 7, 5, 6
• Risperidone 4, 7, 5, 6
• Aripiprazole 4, 5, 8
• Quetiapine 4, 7, 5, 6
• Ziprasidone 4, 5, 6

Key Findings

• Olanzapine, risperidone, and aripiprazole presented advantages for the first-line treatment of first episode of psychosis in terms of effectiveness 4
• Haloperidol, olanzapine, and risperidone were significantly more effective than aripiprazole, quetiapine, and ziprasidone for the acute treatment of psychosis in hospitalized patients with schizophrenia, schizoaffective disorder, or schizophreniform disorder 5
• Olanzapine, quetiapine, and risperidone demonstrated comparable effectiveness in early-psychosis patients, as indicated by similar rates of all-cause treatment discontinuation 7
• Each second-generation antipsychotic has a unique pharmacodynamic and pharmacokinetic profile, allowing for unique dosing strategies to be employed when treating different disorders 8
• Olanzapine might lead to longer treatment continuation in treatment-naive first-episode psychosis patients than haloperidol and, possibly ziprasidone 6