Differential Diagnosis for Spontaneous Hematoma on Hand with Lump
- Single most likely diagnosis
- Hematoma due to trauma: This is the most likely diagnosis as spontaneous hematomas are often caused by minor trauma that the patient may not even remember, and the presence of a lump supports this diagnosis.
- Other Likely diagnoses
- Bleeding disorder (e.g., hemophilia, von Willebrand disease): These conditions can cause spontaneous bleeding and hematoma formation, even with minor trauma.
- Anticoagulant use: Patients on anticoagulant medications (e.g., warfarin, aspirin) are at increased risk of bleeding and hematoma formation.
- Vascular malformation: Abnormalities in blood vessel structure, such as arteriovenous malformations, can cause spontaneous bleeding and hematoma formation.
- Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
- Malignancy (e.g., soft tissue sarcoma): Although rare, a spontaneous hematoma with a lump could be a sign of an underlying malignancy, which would require prompt diagnosis and treatment.
- Infection (e.g., abscess): A spontaneous hematoma could be a sign of an underlying infection, such as an abscess, which would require prompt antibiotic treatment.
- Aneurysm or pseudoaneurysm: A spontaneous hematoma could be a sign of an underlying aneurysm or pseudoaneurysm, which would require prompt surgical intervention.
- Rare diagnoses
- Amyloidosis: This condition can cause spontaneous bleeding and hematoma formation due to the deposition of abnormal proteins in blood vessel walls.
- Scurvy: Vitamin C deficiency can cause spontaneous bleeding and hematoma formation due to impaired collagen synthesis.
- Ehlers-Danlos syndrome: This genetic disorder can cause spontaneous bleeding and hematoma formation due to defects in blood vessel structure.