Do lips have oil glands, specifically sebaceous glands?

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Last updated: January 23, 2026View editorial policy

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Do Lips Have Oil Glands?

Yes, lips do have sebaceous (oil) glands, but their distribution is variable and they are not universally present across the entire lip structure. 1

Anatomical Distribution of Sebaceous Glands on Lips

The presence of sebaceous glands on the lips depends on the specific anatomical zone:

Vermilion Zone (Red Part of Lips)

  • The vermilion zone is characterized as keratinizing glabrous (hairless) epithelium that often contains numerous sebaceous glands, particularly in the upper lip. 1
  • These sebaceous glands on the vermilion border are common in adults and increase in incidence from childhood to adulthood, with slightly higher prevalence in men. 2
  • When sebaceous glands become visible through the epithelium on the vermilion border, they are termed Fordyce's granules (or Fordyce spots). 2

General Facial Skin Context

  • Sebaceous glands are predominantly located on the face and scalp, where they are connected to hair follicles and secrete sebum (oil) to keep skin supple and smooth. 3
  • The majority of sebaceous glands throughout the body are associated with hair follicles, forming pilosebaceous units. 4

Important Clinical Distinctions

What Constitutes Pathologic Findings

  • Only sebaceous glands that are pathologically visible through the epithelium should be regarded as Fordyce's granules—the normal presence of sebaceous glands in lip tissue does not constitute pathology. 2
  • Fordyce's granules typically have the same histological features as cutaneous sebaceous glands and pathologic alterations are rare. 2
  • There is no significant correlation between Fordyce's granules and systemic diseases. 2

Areas Without Sebaceous Glands

  • Sebaceous glands are found throughout the human body except on the palms of the hands and soles of the feet. 5, 6
  • The inner labial mucosa (inside of the lip) contains mucoserous glands rather than sebaceous glands. 1

Clinical Relevance

The sebaceous glands on the lips serve the same functions as those elsewhere on the body:

  • Lubrication of the skin surface 4
  • Thermoregulation 4
  • Antimicrobial activity 4
  • Production of sebum containing characteristic lipids including wax esters and squalene 5

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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