What are the steps to evaluate a Lisfranc injury on x-ray?

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Last updated: January 23, 2026View editorial policy

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Radiographic Evaluation of Lisfranc Injury

Obtain a three-view radiographic series (anteroposterior, oblique, and lateral) as your initial imaging study, with weight-bearing views being absolutely essential for accurate diagnosis. 1, 2

Step-by-Step X-ray Evaluation Protocol

1. Initial Radiographic Views

  • Obtain three standard views: anteroposterior (AP), oblique, and lateral projections of the foot 1
  • Add a fourth AP view with 20° craniocaudal angulation to improve visualization of the Lisfranc joint 1, 2
  • Weight-bearing radiographs are mandatory when the patient can tolerate them—non-weight-bearing images are unreliable and will miss subtle injuries 1, 2
  • Include bilateral foot imaging on AP views to compare the injured side with the uninjured contralateral foot for detecting subtle malalignment 1, 2

2. Key Radiographic Findings to Identify

Primary Signs of Lisfranc Injury:

  • Diastasis between the first and second metatarsal bases: Look for widening of the space between M1 and M2 bases 1, 2, 3
  • The "fleck" sign: A small avulsion fracture fragment in the first-second intermetatarsal space, representing avulsion of the Lisfranc ligament 1, 2, 3

Alignment Assessment:

  • On AP view: The medial border of the second metatarsal base should align with the medial border of the middle cuneiform 1
  • On oblique view: The medial border of the fourth metatarsal base should align with the medial border of the cuboid 1
  • On lateral view: Assess for dorsal displacement of the metatarsal bases relative to the cuneiforms 1

3. Critical Pitfall to Avoid

Never rely solely on non-weight-bearing radiographs—this is the most common reason for missed diagnoses, as purely ligamentous injuries without diastasis will not be visible without weight-bearing stress 1. If the patient cannot bear weight due to pain or other injuries, proceed directly to advanced imaging rather than accepting negative non-weight-bearing films 1.

4. When to Proceed to Advanced Imaging

CT Imaging Indications:

  • When radiographs are normal but clinical suspicion remains high (midfoot pain, swelling, plantar ecchymosis, inability to bear weight) 1
  • For acute hyperflexion injuries or high-energy polytrauma 1
  • When multiple metatarsal and cuneiform fractures are present 1
  • To evaluate the true extent of osseous injury and detect nondisplaced fractures 1
  • In polytrauma patients: Approximately 25% of midfoot fractures identified on CT are overlooked on radiographs 1

MRI Imaging Indications:

  • For purely ligamentous injuries when radiographs are normal but clinical suspicion persists 1
  • For direct visualization of the Lisfranc ligamentous complex, with 3D volumetric acquisitions superior to standard sequences 1
  • MRI shows high correlation with intraoperative findings for unstable Lisfranc injuries 1

5. Special Patient Populations

  • Neuropathic patients require heightened vigilance as they may be able to bear weight despite significant fractures 1
  • Polytrauma patients warrant a lower threshold for CT imaging given the high rate of missed injuries on plain radiographs 1

The algorithmic approach prioritizes weight-bearing radiographs first, followed by CT for osseous detail when radiographs are equivocal or in high-energy trauma, and MRI specifically for suspected purely ligamentous injuries 1. This stepwise progression maximizes diagnostic accuracy while avoiding the common pitfall of accepting negative non-weight-bearing films in a clinically suspicious presentation.

References

Guideline

Diagnostic Criteria for Lisfranc Fracture of the Foot

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Initial Management of Lisfranc Injury

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2026

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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