What is the recommended dose of Senna (ex-lax, generic name: Sennosides)?

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Last updated: April 16, 2025View editorial policy

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From the FDA Drug Label

Adults and children 12 years and older: 2-3 teaspoons (10 to 15 mL) once a day, 3 teaspoons (15 mL) twice a day 6 to 12 years: 1 to 1 1/2 teaspoons (5 to 7.5 mL) once a day, 1 1/2 teaspoons (7.5 mL) twice a day 2 to 6 years: 1/2 to 3/4 teaspoons (2.5 to 3.75 mL) once a day, 3/4 teaspoon (3.75 mL) once a day under 2 years of age: Consult a doctor

The recommended dose of senna is:

  • 2-3 teaspoons (10 to 15 mL) once a day for adults and children 12 years and older
  • 1 to 1 1/2 teaspoons (5 to 7.5 mL) once a day for children 6 to 12 years
  • 1/2 to 3/4 teaspoons (2.5 to 3.75 mL) once a day for children 2 to 6 years
  • Consult a doctor for children under 2 years of age 1

From the Research

The recommended dose of senna for children with constipation is typically 17.5 mg/day, with a range of 1.7-150 mg/day, as higher doses of 60 mg/day are associated with an increased risk of perineal blisters 2. When considering the use of senna for constipation in children, it is essential to weigh the potential benefits against the risks. The most recent and highest quality study on this topic, published in 2018, found that senna is a safe treatment option for constipation in children, with the majority of patients experiencing no significant side effects 2. However, the study did note that higher doses of senna were associated with an increased risk of perineal blisters, which can be a significant concern for pediatric patients. Some key points to consider when using senna for constipation in children include:

  • Starting with a low dose and gradually increasing as needed to minimize the risk of side effects
  • Monitoring for signs of perineal blisters, such as redness, swelling, and pain, and adjusting the dose or discontinuing use if necessary
  • Encouraging frequent diaper changes and good hygiene practices to reduce the risk of skin irritation
  • Considering alternative treatment options, such as osmotic laxatives or fiber supplements, if senna is not effective or is associated with significant side effects It is also important to note that senna should be used under the guidance of a healthcare provider, particularly in pediatric patients, to ensure safe and effective use 3. Additionally, other studies have found that senna is effective and safe for use in adults with constipation, with typical doses ranging from 8.6 mg to 17.2 mg of sennosides taken orally at bedtime 4, 5. However, the primary concern in pediatric patients is the potential risk of perineal blisters, which can be mitigated with careful dosing and monitoring.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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