From the Research
Activating natural killer cells can be achieved through a combination of lifestyle modifications and medical approaches, with the most recent and highest quality study suggesting that harnessing NK cells for cancer immunotherapy is a promising area of research 1. To activate natural killer cells, several strategies can be employed, including:
- Regular exercise, such as moderate-intensity activities like brisk walking or cycling for 30 minutes daily, which stimulates NK cell activity
- Adequate sleep of 7-9 hours per night to maintain optimal NK cell function
- A diet rich in fruits, vegetables, and foods containing zinc, selenium, and vitamin D to support NK cell activity
- Stress reduction techniques, such as meditation, yoga, or deep breathing for 15-20 minutes daily, to prevent stress-induced NK cell suppression
- Certain supplements, like medicinal mushrooms, vitamin C, and vitamin D3, may enhance NK cell function, as suggested by recent studies 2, 3 These approaches work by providing essential nutrients for immune function, reducing cortisol levels that can suppress NK cells, and promoting overall immune balance, which is critical for immune surveillance against cancer cells and viral infections, as highlighted in a recent review 4.
The most recent study on the topic, published in 2024, provides a comprehensive overview of NK cell functions, signaling, molecular mechanisms, and clinical utilization, and suggests that engineered NK cells may be a promising approach for cancer immunotherapy 1. In terms of medical approaches, recent studies have explored the use of NK cell therapy, including the use of chimeric antigen receptors (CARs) to enhance NK cell activity against cancer cells 2, 3. Overall, activating natural killer cells is an important aspect of maintaining immune function and preventing disease, and a combination of lifestyle modifications and medical approaches may be the most effective way to achieve this goal, as suggested by the most recent and highest quality study on the topic 1.