How likely is fistulotomy to aggravate the pudendal nerve in a patient with a history of anal fistulas and potential pudendal neuropathy?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: January 26, 2026View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Risk of Pudendal Nerve Injury from Fistulotomy

Fistulotomy does not directly injure the pudendal nerve, as the pudendal nerve runs outside the surgical field of anal fistula surgery. However, fistulotomy causes sphincter muscle damage that can worsen continence in patients with pre-existing pudendal neuropathy.

Anatomic Separation Between Fistulotomy and Pudendal Nerve

  • The pudendal nerve courses through Alcock's canal in the lateral pelvic wall, well outside the operative field during fistulotomy, which involves only the anal sphincter complex and perianal tissues 1
  • Direct pudendal nerve injury from fistulotomy is anatomically implausible and not reported in the literature 1, 2

The Real Risk: Sphincter Damage Compounding Neuropathy

  • Fistulotomy creates sphincter defects that significantly impair continence—internal anal sphincter defects increase from 30.8% to 74.3% after fistula surgery, and external sphincter defects increase from 15.9% to 32.4% 1
  • In patients with pre-existing pudendal neuropathy, any additional sphincter damage from fistulotomy creates a "double hit" mechanism—the nerve cannot compensate for the structural sphincter injury 3
  • Pudendal nerve terminal motor latency measurements do not change after fistulotomy, confirming the nerve itself is not injured by the procedure 1

Continence Outcomes in Patients with Pudendal Neuropathy

  • Patients with bilateral pudendal neuropathy who undergo sphincter surgery (including fistulotomy) still achieve significant improvement in incontinence scores, from 15 preoperatively to 6 at long-term follow-up 3
  • Patients with unilateral pudendal neuropathy achieve even better results, with scores improving from 16.3 to 5.1 3
  • The presence of pudendal neuropathy does not predict worse outcomes after sphincter surgery—both unilateral and bilateral neuropathy groups showed similar good/excellent results (P > 0.05) 3

Critical Risk Factors That Actually Matter

  • Prior fistulotomy history increases the risk of catastrophic incontinence by 5-fold (relative risk = 5.00,95% CI 1.45-17.27) and makes repeat sphincterotomy absolutely contraindicated 4, 5
  • Baseline incontinence before surgery is a stronger predictor of poor outcomes than pudendal nerve status 1, 6
  • Complex fistulas with secondary extensions are associated with treatment failure (P = 0.008) 2

Recommended Approach for Patients with Suspected Pudendal Neuropathy

  • Pudendal nerve terminal motor latency testing is not useful for surgical decision-making, as it does not predict sphincteroplasty outcomes and should not be used to exclude patients from fistulotomy 3
  • For first-time fistulotomy in patients without prior sphincter surgery, proceed with standard surgical indications regardless of pudendal nerve status 7
  • For patients with prior fistulotomy, use only sphincter-preserving approaches (loose non-cutting seton or LIFT procedure) regardless of pudendal nerve status, as the prior surgery history—not the nerve—is the contraindication 4, 8

Common Pitfalls to Avoid

  • Do not order pudendal nerve studies to decide whether to perform fistulotomy—the nerve is not at risk from the procedure, and test results do not predict outcomes 1, 3
  • Do not assume pudendal neuropathy is a contraindication to sphincter surgery—correction of anatomic defects provides significant benefit even with documented neuropathy 3
  • Avoid aggressive probing or dilation during fistula surgery, as these maneuvers cause iatrogenic sphincter injury, not nerve injury 4

References

Research

Fistulotomy in the tertiary setting can achieve high rates of fistula cure with an acceptable risk of deterioration in continence.

Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2013

Guideline

Management of Low Transsphincteric Fistulas

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2026

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Safety of Anal Sex After Fistulotomy

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2026

Related Questions

Is it normal to feel like defecating out the side of the fistulotomy site after undergoing a fistulotomy procedure?
What treatment options are available for a male patient with a history of fistulotomy, who now experiences tension and loss of sexual sensation without pain, which he attributes to guarding and being over-focused?
What is the best course of action for an adult patient with a history of anorectal surgery and a previously successfully treated fistula with fistulotomy 6 months ago, now presenting with a new fistula?
Can a male patient with a history of fistulotomy and less than 30% anal sphincter division safely return to pre-surgical levels of anal play, given that scar tissue is mechanically stronger?
What are the best management options for persistent fullness, numbness, and blunted sensations in the pelvic area, specifically at the site of a previous fistulotomy?
Can fatigue or insomnia be related to pudendal neuropathy or a previous fistulotomy (surgical procedure for anal fistula) in a patient?
What is the recommended approach for monitoring and adjusting Keppra (Levetiracetam) levels in a patient with a history of seizures or epilepsy, considering age, weight, and renal function?
What are the top choices for antibiotics to treat an uncomplicated urinary tract infection (UTI) in an otherwise healthy adult?
What is the recommended treatment approach for a pediatric or young adult patient with ganglioneuroblastoma?
What is the primary treatment approach for a child diagnosed with diabetes?
What is the best management approach for an elderly patient with a history of fracture, considering their comorbidities such as dementia, diabetes, or cardiovascular disease, and potential osteoporosis?

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.