What amino acid should be avoided during an oral herpes (Herpes Simplex Virus) outbreak?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: April 16, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

From the Research

During an oral herpes outbreak, it's crucial to limit your intake of the amino acid arginine while increasing lysine consumption to potentially reduce the severity and duration of the outbreak. Arginine can promote herpes simplex virus replication, potentially worsening or prolonging outbreaks. Foods high in arginine that you should avoid include nuts (especially almonds, Brazil nuts, and walnuts), chocolate, oats, wheat germ, sesame and sunflower seeds, and gelatin. Instead, focus on consuming more lysine-rich foods like dairy products, fish, chicken, beef, eggs, and legumes, as lysine may help inhibit viral replication by competing with arginine. Some people find taking lysine supplements (typically 1000-3000 mg daily during outbreaks) helpful, though you should consult with a healthcare provider before starting any supplement regimen. This dietary adjustment works because the herpes virus requires arginine for replication, while lysine competitively inhibits arginine's availability to the virus. Key points to consider:

  • Limit arginine intake from foods like nuts, chocolate, and oats
  • Increase lysine consumption from foods like dairy, fish, and legumes
  • Consider lysine supplements, but consult a healthcare provider first
  • Remember that dietary changes should complement, not replace, conventional treatments like antiviral medications for managing herpes outbreaks, as discussed in studies like 1.

References

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.