From the Guidelines
Tomatoes are generally not inflammatory for most people and are actually considered anti-inflammatory due to their rich content of antioxidants, particularly lycopene. This powerful antioxidant helps reduce inflammation in the body and has been linked to decreased risk of chronic inflammatory diseases 1. Tomatoes also contain vitamin C, potassium, and other beneficial compounds that support overall health and can help combat inflammation. However, some individuals may experience inflammatory responses to tomatoes if they have specific sensitivities or conditions. People with nightshade sensitivities, certain autoimmune conditions like rheumatoid arthritis, or those with acid reflux might find that tomatoes trigger inflammation or discomfort for them personally.
According to a recent study published in Gastroenterology, tomatoes are actually included in the CDEDa diet, which is a whole foods diet designed to limit foods that may adversely affect the microbiome or alter intestinal barrier function 1. This suggests that tomatoes are not typically considered inflammatory and can be a part of a healthy diet. If you suspect tomatoes cause inflammation in your body, consider eliminating them from your diet for 2-3 weeks and then reintroducing them while monitoring your symptoms to determine your individual response. For most people though, incorporating tomatoes into a balanced diet can actually help reduce overall inflammation rather than cause it.
Some key points to consider:
- Tomatoes are rich in antioxidants, particularly lycopene, which can help reduce inflammation in the body
- Tomatoes are included in the CDEDa diet, which is designed to limit foods that may adversely affect the microbiome or alter intestinal barrier function
- Some individuals may experience inflammatory responses to tomatoes if they have specific sensitivities or conditions, such as nightshade sensitivities or autoimmune conditions like rheumatoid arthritis
- Incorporating tomatoes into a balanced diet can help reduce overall inflammation rather than cause it, for most people.
From the Research
Inflammatory Effects of Tomatoes
- Tomatoes are rich in lycopene, a potent antioxidant that can prevent the production of inflammatory cytokines 2
- Consumption of tomato juice has been shown to reduce systemic inflammation in overweight and obese females by decreasing serum concentrations of IL-8 and TNF-α 2
- A systematic review and meta-analysis of clinical trials found that tomato intake can significantly reduce TNF-α levels, but has no significant effect on serum CRP and IL-6 concentrations 3
Anti-Inflammatory Properties
- Tomatoes contain anti-inflammatory compounds that can help reduce the risk of inflammatory diseases such as CVD and diabetes 2
- An anti-inflammatory diet rich in omega-3 fatty acids, polyphenols, and colorful, nonstarchy vegetables, including tomatoes, can help stabilize insulin and reduce intake of omega-6 fatty acids, leading to a reduction in inflammation 4
- Tomatoes have been shown to have antioxidant, anti-inflammatory, and anticancer activities, making them a beneficial addition to a healthy diet 5
Potential Risks and Considerations
- While tomatoes are generally safe to eat, individual consumption and sensitivity can vary, and some people may experience adverse effects such as gastroesophageal reflux disease, allergies, or kidney and cardiovascular disorders 5
- The synthesis and accumulation of bioactive molecules in tomatoes can depend on environmental conditions, which may affect their beneficial or harmful effects on human health 5