Is Lorazepam (Ativan) used for treating headaches?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: April 17, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

From the Research

Ativan (lorazepam) is not typically used or recommended for treating headaches, as it is a benzodiazepine medication primarily prescribed for anxiety disorders, insomnia, seizures, and as a pre-surgical sedative. For headaches, first-line treatments include over-the-counter pain relievers like acetaminophen (Tylenol), ibuprofen (Advil, Motrin), or naproxen (Aleve) 1. For migraines specifically, triptans such as sumatriptan or preventive medications like certain antihypertensives, antidepressants, or anti-seizure drugs are more appropriate. Ativan works by enhancing the effect of GABA, a neurotransmitter that inhibits brain activity, which helps reduce anxiety but doesn't address the underlying causes of headaches.

Some key points to consider when treating headaches include:

  • The use of antidepressants for headache prophylaxis, with tricyclic antidepressants like amitriptyline being well-documented for their efficacy in treating migraine and chronic tension-type headache (TTH) 2
  • The importance of addressing comorbid conditions, such as anxiety and depression, which are prevalent in patients suffering from headaches 1, 3
  • The potential benefits of cognitive behavioral therapy (CBT) in improving symptoms of headaches, depression, anxiety, and quality of life in patients with comorbid migraine and/or tension-type headache and major depressive disorder 3

Additionally, benzodiazepines like Ativan carry risks of dependence, tolerance, and withdrawal symptoms with regular use, making them unsuitable for recurring headache management. If you're experiencing headaches, it's best to consult with a healthcare provider who can recommend appropriate treatment options based on your specific headache type and symptoms.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.