Can pediatric patients develop nephrolithiasis (kidney stones)?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: February 15, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

From the Guidelines

Yes, pediatric patients can develop nephrolithiasis (kidney stones).

Overview of Nephrolithiasis in Pediatric Patients

  • Nephrolithiasis, or kidney stones, is a condition that can affect individuals of all ages, including pediatric patients 1.
  • The incidence of pediatric stone disease is lower than in adults, but it is still commonly seen in busy pediatric practices 1.
  • Pediatric patients with urolithiasis may present with symptoms such as abdominal pain and hematuria, although some may not exhibit classic symptoms 1.
  • Affected children may have a family history of nephrolithiasis or predisposing inborn metabolic disease 1.

Risk Factors and Management

  • Certain factors, such as the use of topiramate or a ketogenic diet for the treatment of epilepsy, and immobility in patients with severe neurological involvement, may increase the risk of kidney stone formation in pediatric patients with tuberous sclerosis complex (TSC) 1.
  • Biochemical monitoring of urine may be beneficial in detecting an increased risk of kidney stone formation in these patients 1.
  • For pediatric patients with ureteral stones, treatment options include ureteroscopy (URS) or extracorporeal shock wave lithotripsy (ESWL), with stone-free rates reported to be relatively high for both procedures 1.

Treatment Outcomes

  • A systematic review and meta-analysis comparing the outcomes of flexible ureteroscopy (FURS) and ESWL for upper tract stones in pediatric patients found that both treatments have high success rates, although the evidence is still limited 1.
  • The choice of treatment may depend on patient-specific factors, such as anatomy and body habitus, as well as the size and location of the stone 1.

From the Research

Pediatric Nephrolithiasis

  • Pediatric patients can develop nephrolithiasis, also known as kidney stones, as evidenced by studies showing an increasing incidence of kidney stone disease in children and adolescents 2, 3, 4, 5, 6.
  • The etiology of kidney stones in children can be identified in most cases, with metabolic factors such as hypercalciuria and hypocitraturia, urinary tract infection, and urinary stasis being leading causes 4, 5, 6.
  • Environmental and dietary factors, including excessive dietary sodium, reduced fluid intake, and high consumption of fructose-containing energy drinks, may also contribute to the development of kidney stones in children 3, 4, 6.
  • The evaluation of pediatric nephrolithiasis typically includes a comprehensive history, examination, basic imaging, metabolic evaluation, and genetic testing 6.
  • The recurrence risk for kidney stone occurrence in children is high, with approximately 50% of children presenting with symptomatic recurrence within 3 years of the first stone 2.
  • The management of nephrolithiasis in children requires a multidisciplinary approach, involving pediatricians, pediatric nephrologists, urologists, dietitians, and nurses, and prioritizing prevention and accurate diagnosis is crucial for optimal management 6.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Pediatric Stone Disease: Current Trends and Future Directions.

The Urologic clinics of North America, 2023

Research

Nephrolithiasis in children.

Pediatric nephrology (Berlin, Germany), 2005

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.