Magnesium Glycinate 120mg and Cardiac Arrhythmias
Magnesium glycinate 120mg will not cause skipped heartbeats in a patient with optimal blood pressure and no cardiac history; in fact, magnesium supplementation is used therapeutically to prevent and treat cardiac arrhythmias, particularly in the context of magnesium deficiency.
Magnesium's Role in Cardiac Rhythm
Magnesium is essential for normal cardiac electrical activity and is actively used in clinical practice to prevent and treat cardiac arrhythmias rather than cause them 1.
The German Society for Magnesium Research specifically recommends magnesium administration for prevention of arrhythmias and therapeutic use in patients with rhythm disturbances, both with and without documented magnesium deficiency 1.
Intravenous magnesium is a standard treatment for torsades de pointes (a life-threatening arrhythmia), effectively suppressing episodes even when serum magnesium levels are normal 2.
Concurrent administration of magnesium with certain antiarrhythmic drugs has been associated with enhanced efficacy and safety in managing arrhythmias 2.
Safety Profile of Oral Magnesium Supplementation
Oral magnesium administration is considered very safe according to expert consensus 1.
The dose of 120mg magnesium glycinate is well below therapeutic doses used for arrhythmia prevention and represents a standard supplementation amount.
When magnesium is given parenterally (intravenously) at high doses, monitoring is recommended, but oral supplementation at standard doses does not require such precautions 1.
Context of Current Medications
Losartan 50mg
Your current losartan dose is actually suboptimal for cardiovascular protection—clinical trials demonstrate that 100mg daily provides superior outcomes compared to 50mg daily 2, 3, 4.
Losartan has a favorable drug interaction profile with no clinically relevant interactions with most medications 5.
There is no documented interaction between losartan and magnesium supplementation that would predispose to arrhythmias.
Clonazepam 0.5mg Twice Daily
Benzodiazepines like clonazepam do not have significant cardiac conduction effects at therapeutic doses.
The only cardiac concern with clonazepam would be in massive overdose scenarios combined with other CNS depressants 6, which is not relevant to your therapeutic dosing.
What Actually Causes "Skipped Heartbeats"
If you are experiencing palpitations or perceived skipped beats, consider these more likely causes:
Premature atrial or ventricular contractions (PACs/PVCs): Common benign arrhythmias often triggered by caffeine, stress, or fatigue—not magnesium supplementation.
Suboptimal losartan dosing: Your current 50mg dose may not be providing maximal cardiovascular benefit; increasing to 100mg daily is recommended for better outcomes 3, 4, 7.
Electrolyte imbalances: Magnesium deficiency (not supplementation) is actually a recognized risk factor for cardiac arrhythmias 1.
Clinical Bottom Line
Magnesium glycinate 120mg daily is safe and will not cause cardiac arrhythmias. If you are experiencing palpitations or skipped beats, they are unrelated to this magnesium supplement and should be evaluated independently. In fact, if you have underlying magnesium deficiency, supplementation may actually reduce arrhythmia risk 1.
The more pressing issue is that your losartan 50mg dose is likely inadequate—clinical evidence strongly supports increasing to 100mg daily for optimal cardiovascular protection 2, 3, 4, 7.