What is the efficacy of plasma (plasma) pen fibroblast treatment?

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Last updated: February 15, 2025 • View editorial policy

From the Research

Efficacy of Plasma Pen Fibroblast Treatment

The efficacy of plasma pen fibroblast treatment is a topic of interest, with various studies examining its effects and potential complications.

  • The treatment has been associated with several complications, including burns and chemical eye injuries, as reported in case studies 1, 2.
  • However, other studies have investigated the use of plasma and fibroblasts in skin rejuvenation and wound repair, with promising results 3, 4, 5.

Complications and Safety

  • A case report published in Cureus described a second-degree burn caused by a non-standard aesthetic procedure using a PlasmaPen Fibroblast 1.
  • Another case report published in BMC Ophthalmology described a bilateral chemical eye injury following plasma fibroblast skin tightening treatment secondary to EMLA cream 2.

Alternative Uses of Plasma and Fibroblasts

  • A study published in the Journal of Cosmetic and Laser Therapy reported the long-term clinical efficacy and safety of an autologous dermal filler based on cultured fibroblasts and plasma gel for facial wrinkles 3.
  • Research published in the Journal of Biological Regulators and Homeostatic Agents evaluated the effect of platelet-rich plasma on fibroblast primary culture and found an up-regulation of genes involved in bio-revitalization 4.
  • A study published in the International Journal of Molecular Sciences developed an integrated preparation method for platelet-rich plasma and investigated its dose-response relationship with tissue regeneration, finding that PRP with a (2×) enrichment ratio was most effective in promoting fibroblast proliferation and skin wound healing 5.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.