Treatment of Bell's Palsy in Adults
Prescribe oral corticosteroids within 72 hours of symptom onset—specifically prednisolone 50 mg daily for 10 days or prednisone 60 mg daily for 5 days followed by a 5-day taper—as this is the only proven effective treatment that significantly improves facial nerve recovery. 1
Immediate Management (Within 72 Hours)
Corticosteroid Therapy: The Cornerstone
- Start prednisolone 50 mg daily for 10 days OR prednisone 60 mg daily for 5 days with a 5-day taper 1
- Evidence demonstrates 83% recovery at 3 months with prednisolone versus 63.6% with placebo, and 94.4% recovery at 9 months versus 81.6% with placebo 1
- Treatment beyond 72 hours has no proven benefit and should not be initiated 1
Antiviral Therapy: Optional Add-On Only
- Never prescribe antivirals alone—they are completely ineffective as monotherapy 1, 2
- May offer valacyclovir 1 g three times daily for 7 days OR acyclovir 400 mg five times daily for 10 days in combination with corticosteroids 1, 2
- The added benefit is minimal (96.5% complete recovery with combination versus 89.7% with steroids alone), but risks are low 1
- This is an option, not a recommendation—corticosteroids remain the essential treatment 1
Eye Protection: Critical and Non-Negotiable
- Apply lubricating ophthalmic drops every 1-2 hours while awake 1
- Use ophthalmic ointment at bedtime for sustained moisture retention 1
- Tape or patch the eye at night with careful instruction to avoid corneal abrasion 1
- Prescribe sunglasses for outdoor use to protect against wind and particles 1
- Consider moisture chambers (polyethylene covers) for severe cases 1
- Refer urgently to ophthalmology if complete inability to close the eye or any signs of corneal exposure develop 1
Diagnosis Confirmation
Clinical Features Required
- Acute onset of unilateral facial weakness developing over less than 72 hours 1, 2
- Forehead involvement (inability to wrinkle forehead or raise eyebrow on affected side) distinguishes this from stroke 3
- May have ipsilateral ear pain, taste disturbance, hyperacusis, or dry eye 1, 4
Exclude Alternative Diagnoses
- Document function of all cranial nerves—any additional cranial nerve involvement excludes Bell's palsy 4, 3
- Check for limb weakness, speech difficulties, or altered consciousness—their presence indicates stroke 3
- Assess for bilateral facial weakness—this is extremely rare in Bell's palsy and suggests Guillain-Barré syndrome, Lyme disease, or sarcoidosis 4, 3
No Routine Testing Needed
- Do not order laboratory tests or imaging for typical presentations 1, 4
- MRI with and without contrast is reserved for atypical features: recurrent paralysis on same side, isolated branch paralysis, other cranial nerve involvement, or no recovery after 3 months 1, 4
Therapies to Avoid
Do not recommend physical therapy, acupuncture, or surgical decompression—these have no proven benefit over spontaneous recovery. 1, 5
Follow-Up Algorithm
Early Follow-Up (1-2 Weeks)
- Assess recovery trajectory and reinforce eye protection 1
- Monitor for complications or new neurologic findings 1
Mandatory Reassessment Triggers
- Refer immediately if new or worsening neurologic findings develop at any point 1
- Refer immediately if ocular symptoms develop at any point 1
- Refer to facial nerve specialist if incomplete recovery at 3 months 1
- Progressive weakness beyond 3 weeks is a red flag requiring immediate reassessment 1
Long-Term Considerations
- Approximately 70% of patients with complete paralysis recover fully within 6 months 1, 6
- Patients with incomplete paralysis have up to 94% recovery rates 1
- 30% may experience permanent facial weakness requiring reconstructive options 1
Common Pitfalls
- Delaying corticosteroids beyond 72 hours eliminates their effectiveness 1
- Prescribing antivirals alone is completely ineffective and delays appropriate treatment 1, 2
- Inadequate eye protection can cause permanent corneal damage 1
- Missing forehead involvement leads to misdiagnosis of stroke as Bell's palsy 3
- Failing to refer at 3 months delays access to reconstructive surgery and psychological support 1