What are the discharge instructions for a patient with influenza A?

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Last updated: January 29, 2026View editorial policy

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Discharge Instructions for Influenza A

Patients with influenza A should expect illness resolution within 7 days, but must remain vigilant for warning signs requiring immediate medical attention, practice strict infection control measures, and understand when antiviral therapy is beneficial. 1

Expected Illness Course and Recovery Timeline

  • The acute illness typically resolves within 7 days, though cough, malaise, and fatigue commonly persist for several weeks after the acute phase. 1
  • This prolonged recovery is normal and does not necessarily indicate complications, though persistent or worsening symptoms warrant re-evaluation. 1

Warning Signs Requiring Immediate Medical Attention

Seek urgent care immediately if you develop any of the following:

  • Respiratory distress: increasing shortness of breath, respiratory rate >30 breaths/min, or difficulty breathing 2
  • Persistent high fever: temperature >37.8°C (100°F) lasting more than 4 days 2
  • Hemodynamic instability: heart rate >100 beats/min, systolic blood pressure <90 mmHg, or signs of shock 2
  • Hypoxia: oxygen saturation <90% or cyanosis (bluish discoloration of skin) 2
  • Neurological changes: altered mental status, confusion, or drowsiness 2
  • Severe dehydration: inability to maintain oral intake or vomiting for more than 24 hours 2
  • Worsening after initial improvement: recrudescent fever or increasing shortness of breath suggesting bacterial superinfection 2, 1

Infection Control and Preventing Transmission to Others

Hand hygiene is the single most effective measure to prevent spread:

  • Wash hands thoroughly with soap and water or use alcohol-based hand sanitizer, particularly after coughing or sneezing. 2, 1, 3
  • If hands are visibly soiled, soap and water is superior to alcohol-based sanitizers. 2, 3

Practice respiratory etiquette:

  • Cover your nose and mouth with a tissue when coughing or sneezing, and dispose of the tissue immediately. 2, 1, 3
  • If no tissue is available, cough or sneeze into your elbow (not your hands). 1, 3
  • Wear a surgical mask if you must be around others, especially in common areas. 2, 3

Isolation and activity restrictions:

  • Stay home and avoid contact with others, especially high-risk individuals (elderly, pregnant women, immunocompromised), until you are fever-free for 24 hours without using fever-reducing medications. 2, 1, 3
  • Remain off work while symptomatic to prevent transmission to colleagues. 1, 3
  • Maintain at least 3 feet of separation from others when isolation is not possible. 2, 3

Antiviral Medication Information

If you were prescribed oseltamivir (Tamiflu):

  • Take 75 mg twice daily for 5 days as prescribed. 2
  • Oseltamivir is most effective when started within 48 hours of symptom onset, ideally within 24 hours, and reduces illness duration by approximately 24 hours. 2, 1, 4
  • Take with food to reduce nausea, the most common side effect. 5, 6
  • Complete the full 5-day course even if you feel better. 2
  • If you have kidney disease (creatinine clearance <30 mL/min), your dose should be reduced to 75 mg once daily. 2

If you were NOT prescribed antivirals:

  • Antivirals are most beneficial when started within 48 hours of symptom onset. 2, 1
  • For future episodes, consider having a prescription ready to start at the first sign of symptoms if you are at high risk for complications. 1

Antibiotic Use: When They Are NOT Needed

Antibiotics are NOT routinely needed for uncomplicated influenza with acute bronchitis in previously healthy adults. 2, 1

Antibiotics should only be considered if:

  • You develop worsening symptoms after initial improvement (recrudescent fever or increasing shortness of breath), suggesting bacterial superinfection. 2, 1
  • You are at high risk of complications and develop lower respiratory tract features. 2

Medication Safety

If using over-the-counter decongestants:

  • Afrin (oxymetazoline) or similar nasal decongestant sprays should NOT be used for more than 3 consecutive days to avoid rebound congestion. 1

Fever-reducing medications:

  • Acetaminophen or ibuprofen may be used to reduce fever and relieve body aches as needed.
  • Remember: you must be fever-free for 24 hours WITHOUT using these medications before returning to work or normal activities. 2, 1, 3

Follow-Up Care

No routine follow-up is needed for uncomplicated cases in previously healthy adults. 1

Self-monitor for warning signs and seek care if:

  • Symptoms worsen or fail to improve after 7 days. 1
  • Any of the warning signs listed above develop. 2, 1

For patients with chronic conditions:

  • Follow-up clinical review should be considered if you suffered significant complications or worsening of underlying disease, either with your primary care provider or in a hospital clinic. 2

Prevention for Future Influenza Seasons

Annual influenza vaccination is recommended for all adults and is the most effective prevention strategy. 2, 1, 7

  • Vaccination should be obtained before the next influenza season, even though it won't help with your current infection. 1
  • If you are unvaccinated, consider getting the vaccine now for protection against future exposures during the current influenza season. 7

Household Contacts and Exposure

If household members develop symptoms:

  • They should seek medical attention promptly, as antiviral treatment is most effective when started within 24-48 hours of symptom onset. 2, 1, 7
  • High-risk household contacts (elderly, pregnant, immunocompromised, chronic medical conditions) may benefit from antiviral prophylaxis with oseltamivir 75 mg once daily for 10 days. 7

Common Pitfalls to Avoid

  • Do not stop isolation prematurely: You remain contagious for approximately 5 days after symptom onset, and potentially longer if immunocompromised. 2
  • Do not rely solely on feeling better: You must be fever-free for 24 hours without fever-reducing medications before ending isolation. 2, 1, 3
  • Do not demand antibiotics: They will not help viral influenza and may cause unnecessary side effects and antibiotic resistance. 2, 1

References

Guideline

Influenza A Management and Prevention

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Influenza Precautions and Control Measures

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Influenza: Diagnosis and Treatment.

American family physician, 2019

Guideline

Post-Exposure Management for Asymptomatic Household Contact of Influenza A

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2026

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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